Obesity vaccines

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2014

Autores

Monteiro, M (Autor) ICBAS

Revista

A Revista está pendente de validação pelos Serviços Administrativos.

Título: HUMAN VACCINES & IMMUNOTHERAPEUTICS

Vol. 10

Páginas: 887-895

ISSN: 2164-5515

Editora: Landes Bioscience

Indexação

ISI Web of Knowledge - 6 Citações

Scopus - 9 Citações

Outras Informações

ID Authenticus: P-009-HZW

DOI: 10.4161/hv.27537

Abstract (EN): Obesity is one of the largest and fastest growing public health problems in the world. Last century social changes have set an obesogenic milieu that calls for micro and macro environment interventions for disease prevention, while treatment is mandatory for individuals already obese. The cornerstone of overweight and obesity treatment is diet and physical exercise. However, many patients find lifestyle modifications difficult to comply and prone to failure in the long-term; therefore many patients consider anti-obesity drugs an important adjuvant if not a better alternative to behavioral approach or obesity surgery. Since the pharmacological options for obesity treatment remain quite limited, this is an exciting research area, with new treatment targets and strategies on the horizon. This review discusses the development of innovative therapeutic agents, focusing in energy homeostasis regulation and the use of molecular vaccines, targeting hormones such as somatostatin, GIP and ghrelin, to reduce body weight.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9