Morphological transition of Helicobacter pylori adapted to water

• Tipo: Artigo em Revista Científica Internacional
• Data: 2017

Autores

Fernandes, RM (Autor) Outra; Silva, H (Autor) Outra; Ricardo Jorge Dinis Oliveira (Autor) FMUP; Almeida, C (Autor) Outra; Azevedo, NF (Autor) ICBAS; Vieira, MJ (Autor) Outra

Revista

Título: Future Microbiology

Vol. 12

Páginas: 1167-1179

ISSN: 1746-0913

Editora: Future Medicine Ltd.

Indexação

ISI Web of Knowledge - 4 Citações

Scopus - 4 Citações

Outras Informações

ID Authenticus: P-00N-3E5

DOI: 10.2217/fmb-2016-0174

Abstract (EN): Aim: This study aims to investigate the morphological transition of Helicobacter pylori during adaptation to water. Materials & methods: Different strains were adapted to water. Changes regarding cultivability and cellular morphology were recorded. Expression of 11 genes involved in H. pylori morphological changes was evaluated by real-time PCR. Results: H. pylori presented increased cultivability in water after adaptation. The permanent loss of the spiral shape was observed, but no transition into coccoid form has occurred. Expression levels of genes involved in peptidoglycan assembly of H. pylori 26695 have shown significant changes between adapted and nonadapted strains. Conclusion: Adaption to water favors the culturable phenotype and the morphological transition to the rod shape, into a process that implicates the peptidoglycan turnover.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 13