Impact of a School-Based Intervention Protocol-ACORDA Project-On Adipokines in an Overweight and Obese Pediatric Population

• Tipo: Artigo em Revista Científica Internacional
• Data: 2016

Autores

Henrique Nascimento (Autor) Outra; Ana Inês Alves (Autor) Outra; Ana Filipa Medeiros (Autor) Outra; Susana Coimbra (Autor) Outra; Cristina Catarino (Autor) FFUP; Elsa Bronze-da-Rocha (Autor) FFUP; Elísio Costa (Autor) FFUP; Petronila Rocha-Pereira (Autor) Outra; Gustavo Silva (Autor) Outra; Luísa Aires (Autor) Outra; André Seabra (Autor) FADEUP; Jorge Mota (Autor) FADEUP; Helena Ferreira Mansilha (Autor) Outra; Carla Rêgo (Autor) Outra; Alice Santos-Silva (Autor) FFUP; Luis Belo (Autor) FFUP

Revista

Título: Pediatric Exercise Science

Vol. 28 Nº 3

Páginas: 407-416

ISSN: 0899-8493

Editora: Human Kinetics Publishers, Inc.

Indexação

ISI Web of Knowledge - 17 Citações

Scopus - 19 Citações

Classificação Científica

FOS: Ciências sociais

Outras Informações

ID Authenticus: P-00K-NZM

DOI: 10.1123/pes.2015-0261

Abstract (EN): Purpose: There are few reliable studies assessing the effect of physical exercise (PE) on adipokines levels at young ages. Our objective was to study the effects of regular PE on plasma adipokines in pediatric overweight and obesity. Method: 117 overweight and obese children and adolescents (47% females; 10.2 years) participated in an 8-month longitudinal study divided in two groups: PE group (n = 80), engaged in an after-school PE program; control group (n = 37), with no PE program. Plasma lipids, C-reactive protein (CRP), adiponectin, resistin, leptin, IL-6, IL-1beta, TNF-alpha, insulin and glucose levels were determined. Results: contrarily to the control group, the PE group presented reductions in body mass index z-score (BMIzsc) and body fat percentage that were accompanied by an improvement in lipid profile and insulin resistance, a reduction in CRP and TNF-alpha and an increase in adiponectin levels. The reductions in BMIzsc were inversely correlated with changes in adiponectin (r=-0.329, p =.003) and positively correlated with changes in percentage body fat (r =.262, p =.032), triglycerides (r =.228, p =.042) and leptin (r =.285, p =.010). Conclusions: Moderate reductions in adiposity improve proinflammatory status in obese children and adolescents. A more substantial reduction in BMIzsc was associated with a greater increment in adiponectin and reduction in leptin.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 10