NMR metabolomics of renal cancer: an overview

• Tipo: Artigo em Revista Científica Internacional
• Data: 2015

Autores

Gil, AM (Autor) Outra; de Pinho, PG (Autor) FFUP; Monteiro, MS (Autor) Outra; Duarte, IF (Autor) Outra

Revista

Título: Bioanalysis

Vol. 7

Páginas: 2361-2374

ISSN: 1757-6180

Editora: Future Medicine Ltd.

Indexação

ISI Web of Knowledge - 15 Citações

Scopus - 17 Citações

Outras Informações

ID Authenticus: P-00G-QGD

DOI: 10.4155/bio.15.167

Abstract (EN): This paper reviews the use of NMR metabolomics for the metabolic characterization of renal cancer. The existing challenges in the clinical management of this disease are first presented, followed by a brief introduction to the metabolomics approach, in the context of cancer research. A subsequent review of the literature on NMR metabolic studies of renal cancer reveals that the subject has been clearly underdeveloped, compared with other types of cancer, particularly regarding cultured cells and tissue analysis. NMR analysis of biofluids has focused on blood (plasma or serum) metabolomics, comprising no account of studies on human urine, in spite of its noninvasiveness and physiological proximity to the affected organs. Finally, some areas of potential future development are identified.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 14