Chemical Composition and Biological Prospects of Essential Oils and Extracts of Aphyllocladus spartioides Growing in Northwest Argentina

• Tipo: Artigo em Revista Científica Internacional
• Data: 2017

Autores

Liliana Celaya (Autor) Outra; Carmen Viturro (Autor) Outra; Luís R. Silva (Autor) FEUP

Revista

Título: Chemistry and Biodiversity

Vol. 14 Nº 4

ISSN: 1612-1872

Editora: Wiley-Blackwell

Indexação

ISI Web of Science

Scopus

Projetos Associados

LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia

Outras Informações

DOI: 10.1002/cbdv.201600227

Abstract (EN): Aphyllocladus spartioides WEDD. is a native and aromatic herb used in traditional medicine, however it is still poorly investigated. In this work, the volatile profile of A. spartioides growing in Hornillos-Northwest Argentina was determined by GC/MS/FID and the phenolic compounds of hydroethanolic and decoction extracts were analyzed by HPLC-DAD. The antibacterial potential, antioxidant activity and a-glucosidase inhibition activity were checked by in vitro assays. The volatile profile allowed the identification of 68 compounds, being a-pinene and cadinene the main ones. Eighteen phenolics were identified, isorhamnetin derivatives and different phenolic acid derivatives were found in higher amounts, mainly in the hydroethanolic extract. A concentration-dependent activity was noticed against DPPH
, O
2 ,
NO and a-glucosidase, these activities being reported for the first time. Hydroethanolic extract was most active against DPPH
,
NO and a-glucosidase (IC50 = 79, 206 and 181 lg/ml). Decoction extract proved to be better against O
2 (IC50 = 20 lg/ml). Regarding the antibacterial activity, hydroethanolic extract was more active compared with decoction and essential oil. MICs of 0.3 – 0.6 mg/ml were obtained against Staphylococcus aureus, Bacillus cereus, and Micrococcus luteus. Results suggest that the extracts of A. spartioides from Northwest Argentina may be interesting to use as a source of natural antioxidants/antimicrobials for pharmaceutical incorporations or food supplementation.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 10