Is the lack of concurrence of bacterial vaginosis and vaginal candidosis explained by the presence of bacterial amines?

• Tipo: Artigo em Revista Científica Internacional
• Data: 1999

Autores

rodrigues, ag (Autor) FMUP; Mardh, PA (Autor) Outra; pina-vaz, c (Autor) FMUP; Martinez de Oliveira, J (Autor) Outra; da Fonseca, AF (Autor) Outra

Revista

Título: American Journal of Obstetrics and Gynecology

Vol. 181

Páginas: 367-370

ISSN: 0002-9378

Editora: Elsevier

Indexação

ISI Web of Knowledge - 18 Citações

Scopus - 29 Citações

Outras Informações

ID Authenticus: P-001-3NW

DOI: 10.1016/s0002-9378(99)70563-6

Abstract (EN): OBJECTIVE and STUDY DESIGN: We report for the first time an inhibitory effect on cell division and germ tube formation by Candida albicans and strains of other Candida species by putrescine and cadaverine. RESULTS: Both bacterial amines showed a dose-dependent inhibition of germ tube formation by C albicans, as well as budding (inhibition of cell division) of strains of other Candida species (ie, C glabrata, C krusei, and C tropicalis). CONCLUSIONS: We hypothesize that the presence of these and possibly other bacterial amines produced by anaerobes in the vaginal flora and seen in bacterial vaginosis, as in the healthy gut, may explain why candidosis is rarely seen in these instances.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4