Characterization of Neovascular Age-Related Macular Degeneration Patients with Outer Retinal Tubulations

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

Faria Correia, F (Autor) Outra; Barros Pereira, R (Autor) Outra; Queiros Mendanha, L (Autor) Outra; Fonseca, S (Autor) Outra; Mendonca, L (Autor) Outra; Manuel Falcão (Autor) FMUP; Brandao, E (Autor) Outra; Falcão-Reis F (Autor) FMUP; Ângela Carneiro (Autor) FMUP

Revista

Título: Ophthalmologica

Vol. 229

Páginas: 147-151

ISSN: 0030-3755

Editora: Karger

Indexação

ISI Web of Knowledge - 24 Citações

Scopus - 34 Citações

Outras Informações

ID Authenticus: P-005-3G2

DOI: 10.1159/000346854

Abstract (EN): Purpose: To characterize the neovascular lesions of patients with age-related macular degeneration (AMD) and outer retinal tubulations (ORTs). Methods: A retrospective study of 377 eyes with exudative AMD, submitted to intravitreal anti-angiogenic treatment. Patients were divided into 2 groups according to the presence or absence of ORTs on spectral-domain optical coherence tomography (SD-OCT; group 1 - with ORTs; group 2 - without ORTs). Age, best corrected visual acuity (BCVA), fluorescein angiography characteristics, presence of subretinal fibrosis and subfoveal photoreceptor integrity on SD-OCT were analyzed. Results: Although both groups had a BCVA gain during the follow-up period, initial and final BCVA were lower in group 1 (p = 0.020 and p = 0.042, respectively). There was no statistically significant difference in the BCVA variation between the 2 groups (p = 0.907). Regarding the initial angiographic lesion type, there was a statistically significant difference between the 2 groups (p = 0.008): group 1 had more lesions with a classic component and group 2 had more occult lesions with no classic component. There was a statistically significant difference concerning the loss of subfoveal photoreceptor integrity (p = 0.0007). Conclusions: Even though AMD patients with ORTs were associated with poor visual outcomes, we reported BCVA improvement. AMD patients with a classical component in their lesions are prone to develop ORTs. Copyright (C) 2013 S. Karger AG, Basel

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5