Terahertz absorption and reflection imaging of carcinoma-affected colon tissues embedded in paraffin

• Tipo: Artigo em Revista Científica Internacional
• Data: 2016

Autores

Wahaia, F (Autor) Outra; Kasalynas, I (Autor) Outra; Venckevicius, R (Autor) Outra; Seliuta, D (Autor) Outra; Valusis, G (Autor) Outra; Urbanowicz, A (Autor) Outra; Molis, G (Autor) Outra; Carneiro F (Autor) FMUP; Carvalho Silva, CDC (Autor) Outra; Granja, PL (Autor) Outra

Revista

Título: Journal of Molecular Structure

Vol. 1107

Páginas: 214-219

ISSN: 0022-2860

Editora: Elsevier

Indexação

ISI Web of Knowledge - 27 Citações

Scopus - 32 Citações

Outras Informações

ID Authenticus: P-00K-0W4

DOI: 10.1016/j.molstruc.2015.11.048

Abstract (EN): In the present study, dehydrated human colon tissues embedded in paraffin were studied at THz frequency. A compact THz imaging system with high numerical aperture optics was developed for the analysis of adenocarcinoma-affected colon sections, in transmission and reflection geometry. A comprehensive analysis of the THz images revealed a contrast up to 23% between the neoplastic and control tissues. Absorption and reflection THz images demonstrated the possibility to distinguish adenocarcinoma-affected areas even without water in the tissue, as the main contrast mechanism in THz measurements has been observed to be water absorption in in vivo or freshly excised tissues. The present results corroborate with previous histologic findings in the same tissues, and confirm that the contrast prevails even in dehydrated tissues.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 6