Effects of Benzo(a)pyrene on Seabass (Dicentrarchus labrax L.): Biomarkers, Growth and Behavior

• Tipo: Artigo em Revista Científica Internacional
• Data: 2009

Autores

Gravato, C (Autor) Outra; Guilhermino, L. (Autor) ICBAS

Revista

Título: Human and Ecological Risk Assessment (HERA)

Vol. 15

Páginas: 121-137

ISSN: 1080-7039

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 24 Citações

Scopus - 29 Citações

Outras Informações

ID Authenticus: P-003-Q8R

DOI: 10.1080/10807030802615659

Abstract (EN): The main purpose of this study was to investigate the effects of benzo( a) pyrene (BaP) on seabass (Dicentrarchus labrax) juveniles using parameters at different levels of biological organization. Liver antioxidant status, BaP biotransformation and accumulation, growth, and behavior were determined in juveniles after 28 d exposure to BaP (1-16 mu g/l). Liver ethoxyresorufin O-deethylase increased in seabass exposed to 1-8 mu g/l of BaP. Liver glutathione S-transferases and catalase activities were significantly increased at 4 and 8 mu g/l, but a slight decrease was observed at the highest concentrations tested. Bile BaP metabolites were significantly different from the control group at 1 and 16 mu g/l BaP. Liver BaP metabolites and lipid peroxidation significantly increased at 8 and 16 mu g/l BaP. These results suggest that BaP metabolites' accumulation induces oxidative damage in seabass liver. Body weight and length increase were significantly reduced in fish exposed to BaP, with LOECs of 16 and 4 mu g/l, respectively. Food intake and swimming velocity were significantly decreased after exposure to BaP, with LOEC values of 16 and 8 mu g/l, respectively. Results suggest that at concentrations of BaP equal or higher than 8 mu g/l, the detoxification capacity decreases, an accumulation of liver BaP metabolites occurs causing lipid peroxidation, affecting growth and swimming capability of fish.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 17