Angiogenesis and breast cancer

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2010

Autores

Fernando Schmitt (Autor) FMUP; Longatto Filho, A (Autor) Outra; Lopes, JM (Autor) FMUP

Revista

Título: Journal of Oncology

Vol. 2010

Páginas: 1-7

ISSN: 1687-8450

Editora: Hindawi

Indexação

Scopus - 93 Citações

Outras Informações

ID Authenticus: P-007-W7C

DOI: 10.1155/2010/576384

Abstract (EN): Angiogenesis is an essential step for breast cancer progression and dissemination. The development of new blood vessels in cancer setting (angiogenesis) is conducted by numerous physiological and pathological stimuli, where the main stimulus is hypoxia. The knowledge of different molecular pathways regulating angiogenesis is constantly growing. An increased and complex scenario of angiogenesis is nowadays available in breast cancer, specifically, and permits not only to understand most of the important phases of neoplastic growth but also offer an exciting perspective for new therapeutic proposals based on blocking new blood vessels sprouting. This review focused on historical and recent understanding of angiogenesis occurrence in breast cancer. Copyright © 2010 Adhemar Longatto Filho et al.

Idioma: Inglês

Tipo (Avaliação Docente): Científica