Metabolomics of cocaine: implications in toxicity

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2015

Autores

Ricardo Jorge Dinis Oliveira (Autor) FMUP

Revista

Título: Toxicology Mechanisms And Methods

Vol. 25

Páginas: 494-500

ISSN: 1537-6516

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 28 Citações

Scopus - 29 Citações

Outras Informações

ID Authenticus: P-00G-PDN

DOI: 10.3109/15376516.2015.1072612

Abstract (EN): Cocaine is the most commonly used illicit drug among those seeking care in Emergency Departments or drug detoxification centers. Cocaine, chemically known as benzoylmethylecgonine, is a naturally occurring substance found in the leaves of the Erythroxylum coca plant. The pharmacokinetics of cocaine is dependent on multiple factors, such as physical/chemical form, route of administration, genetics and concurrent consumption of alcohol. This review aims to discuss metabolomics of cocaine, namely by presenting all known metabolites of cocaine and their roles in the cocaine-mediated toxic effects.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7