From mechanical stimulus to bone formation: A review

• Tipo: Artigo em Revista Científica Internacional
• Data: 2015

Autores

Natacha Rosa (Autor) Outra; Ricardo Simões (Autor) Outra; Fernão D. Magalhães (Autor) FEUP; António Torres Marques (Autor) FEUP

Revista

Título: Medical Engineering & Physics

Vol. 37 Nº 8

Páginas: 719-728

ISSN: 1350-4533

Editora: Elsevier

Indexação

ISI Web of Knowledge - 22 Citações

Scopus - 56 Citações

Projetos Associados

LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia

Outras Informações

ID Authenticus: P-00G-EEC

DOI: 10.1016/j.medengphy.2015.05.015

Abstract (EN): Bone is a remarkable tissue that can respond to external stimuli. The importance of mechanical forces on the mass and structural development of bone has long been accepted. This adaptation behaviour is very complex and involves multidisciplinary concepts, and significant progress has recently been made in understanding this process. In this review, we describe the state of the art studies in this area and highlight current insights while simultaneously clarifying some basic yet essential topics related to the origin of mechanical stimulus in bone, the biomechanisms associated with mechanotransduction, the nature of physiological bone stimuli and the test systems most commonly used to study the mechanical stimulation of bone.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 10