Could condensin scaffold the mitotic chromosome?

• Tipo: Artigo em Revista Científica Internacional
• Data: 2004

Autores

Coelho, PA (Autor) Outra; Queiroz Machado, J (Autor) Outra; Sunkel, CE (Autor) ICBAS

Revista

Título: Cell Cycle

Vol. 3

Páginas: 538-540

ISSN: 1538-4101

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 2 Citações

Scopus - 1 Citação

Outras Informações

ID Authenticus: P-000-AFM

Abstract (EN): One of the most remarkable and yet poorly understood events during the cell cycle is how dispersed chromatin fragments are transformed into chromosomes every time cells undergo mitosis. It has been postulated that mitotic chromosomes might contain an axial scaffold that is involved in condensation but its molecules and structure have remained elusive. Recent data suggests that the condensin complex might indeed be an essential part of the scaffold that provides a platform for other proteins to localize and promote different aspects of chromosome condensation.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3