Immunohistochemical study of the expression of E-cadherin in canine mammary tumours

• Tipo: Artigo em Revista Científica Internacional
• Data: 2003

Autores

Reis, AL (Autor) Outra; carvalheira, j (Autor) ICBAS; Fernando Schmitt (Autor) FMUP; Fátima Gärtner (Autor) ICBAS

Revista

Título: Veterinary Record

Vol. 152

Páginas: 621-624

ISSN: 0042-4900

Editora: Wiley-Blackwell

Indexação

ISI Web of Knowledge - 26 Citações

Scopus - 30 Citações

Outras Informações

ID Authenticus: P-000-GMM

DOI: 10.1136/vr.152.20.621

Abstract (EN): To investigate the possible role of E-cadherin in canine mammary tumours 20 benign and 40 malignant tumours; were evaluated by immunohistochemistry in formalin-fixed paraffin wax-embedded samples. in all the benign tumours, E-cadherin was strongly expressed at the intercellular borders of epithelial cells, but it was less strongly expressed in 17 (43 per cent) of the malignant tumours. Furthermore, poorly differentiated carcinomas were less immunoreactive for E-cadherin than moderately and well differentiated carcinomas.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4