Relationship between body mass index and mean arterial pressure in normotensive and chronic hypertensive pregnant women: a prospective, longitudinal study

• Tipo: Artigo em Revista Científica Internacional
• Data: 2015

Autores

Luis Guedes Martins (Autor) Outra; Mariana Carvalho (Autor) Outra; Catarina Silva (Autor) Outra; Ana Cunha (Autor) Outra; Joaquim Saraiva (Autor) Outra; Filipe Macedo (Autor) Outra; Henrique Almeida (Autor) Outra; Rita Gaio, AR (Autor) FCUP

Revista

Título: BMC Pregnancy and Childbirth

Vol. 15

ISSN: 1471-2393

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 8 Citações

Scopus - 8 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina clínica

Outras Informações

ID Authenticus: P-00J-XW1

DOI: 10.1186/s12884-015-0711-0

Abstract (EN): Background: Being overweight is associated with both higher systolic blood pressure (SBP) and diastolic blood pressure (DBP) during pregnancy and increased risk of gestational hypertensive disorders. The objective of this study was to determine and quantify the effect of body mass index (BMI) on mean arterial pressure (MAP) at several time points throughout pregnancy in normotensive (NT) and chronic hypertensive pregnant (HT) women. Methods: A prospective longitudinal study was carried out in 461 singleton pregnancies (429 low-risk and 32 with chronic arterial hypertension), with measurements taken at the 1st, 2nd, and 3rd trimesters and at delivery. Linear mixed-effects regression models were used to evaluate the time-progression of BMI, SBP, DBP and MAP during pregnancy (NT vs. HT). The longitudinal effect of BMI on MAP, adjusted for the hypertensive status, was investigated by the same methodology. Results: BMI consistently increased with time in both NT and HT women. In contrast, MAP decreased during the first half of pregnancy, after which it increased until the moment of delivery in both groups. A 5-unit increase in BMI was predicted to produce an increase of approximately 1 mmHg in population MAP values. This effect is independent from the time period and from hypertensive status. Conclusions: In both NT and HT pregnant women, MAP is strongly (and significantly) influenced by increases in BMI.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 13