Identification of carbapenem-resistant Acinetobacter baumannii clones using infrared spectroscopy

• Tipo: Artigo em Revista Científica Internacional
• Data: 2014

Autores

Clara Sousa (Autor) Outra; Filipa Grosso (Autor) Outra; Luis Meirinhos Soares (Autor) Outra; Luisa Peixe (Autor) FFUP; Joao Lopes (Autor) Outra

Revista

Título: Journal of Biophotonics

Vol. 7

Páginas: 287-294

ISSN: 1864-063X

Editora: Wiley-Blackwell

Indexação

ISI Web of Knowledge - 17 Citações

Scopus - 27 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Ciências biológicas

Outras Informações

ID Authenticus: P-009-H6B

DOI: 10.1002/jbio.201200075

Abstract (EN): In this work we assessed the discriminatory ability of Fourier-transform Infrared Spectroscopy (FTIR) in 22 representative isolates from a collection of 318 carbapenem-hydrolyzing class D -lactamases (CHDL)-producing Acinetobacter spp. (5 hospitals; 2001-2008) previously characterized by DNA-based typing methods. FTIR spectra were acquired with a Bruker spectrometer and analyzed with support of several chemometric tools. The results showed that FTIR spectroscopy was able to distinguish the main CHDL-producing Acinetobacter baumannii lineages causing infection in Portugal, the ST103 carrying bla(OXA-58), ST98 carrying bla(OXA-24/40)and ST92 carrying bla(OXA-23). Moreover, this study revealed distinctive phenotypic features of A. baumannii lineages causing infections that might justify different epidemic potential. Spectroscopy may arise as a low cost and easily to perform alternative for typing A. baumannii isolates. ((c) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8