Phytochemical investigations and biological potential screening with cellular and non-cellular models of globe amaranth (Gomphrena globosaL.) inflorescences

• Tipo: Artigo em Revista Científica Internacional
• Data: 2012

Autores

Luis R Silva (Autor) Outra; Patricia Valentao (Autor) FFUP; Joana Faria (Autor) Outra; Federico Ferreres (Autor) Outra; Carla Sousa (Autor) FFUP; Angel Gil Izquierdo (Autor) Outra; Brigida R Pinho (Autor) Outra; Paula B Andrade (Autor) FFUP

Revista

Título: Food Chemistry

Vol. 135 Nº 3

Páginas: 756-763

ISSN: 0308-8146

Editora: Elsevier

Indexação

ISI Web of Knowledge - 16 Citações

Scopus - 28 Citações

Classificação Científica

FOS: Ciências agrárias > Outras ciências agrárias

Outras Informações

ID Authenticus: P-002-3EC

DOI: 10.1016/j.foodchem.2012.05.015

Abstract (EN): Gomphrena globosaL. is a popular edible plant used as food colourant and in traditional medicine. In this work, 24 phenolic compounds and eight betacyanins were determined by HPLC-DAD in three different extracts of G. globosa inflorescences. The decoction presented the highest amount of phenolic compounds, kaempferol-3-O-(6-rhamnosyl)hexoside plus kaempferol-3-O-hexoside being the main compounds. The rich betacyanins extract showed isogomphrenin III and gomphrenin III as major metabolites. Decreases in the nitric oxide amounts were observed in LPS-stimulated RAW 264.7 cells. In vitro scavenging micro assays against several reactive species revealed a great antioxidant capacity, particularly against superoxide radical. In general, the best results were obtained with decoction. Some relationships between activity and composition were established. The data provide evidence of the G. globosa inflorescences potential as a source of anti-inflammatory compounds, with relevance for the treatment of acute or chronic inflammatory conditions, and health-promoting antioxidants for use by both food and pharmaceutical industries.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8