The Positive Effect of Moderate Walking Exercise on Chemerin Levels in Portuguese Patients With Type 2 Diabetes Mellitus

• Tipo: Artigo em Revista Científica Internacional
• Data: 2014

Autores

Maria Joao Neuparth (Autor) Outra; Jorge Brandao Proenca (Autor) Outra; Alice Santos Silva (Autor) FFUP; Susana Coimbra (Autor) Outra

Revista

Título: Journal of Investigative Medicine

Vol. 62

Páginas: 350-353

ISSN: 1081-5589

Editora: BMJ PUBLISHING GROUP

Indexação

ISI Web of Knowledge - 14 Citações

Scopus - 17 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina clínica

Outras Informações

ID Authenticus: P-009-NAE

DOI: 10.231/jim.0000000000000025

Abstract (EN): Background: Physical exercise intervention is known to be crucial in the management of type 2 diabetes mellitus (T2DM). We aimed to evaluate, in patients with T2DM, the effect of regular moderate walking exercise on markers of oxidative stress, lipid metabolism, and inflammation. Methods: We studied 30 patients with T2DM who walked regularly during the last year and 53 patients with T2DM who did not perform any type of exercise. The patients were evaluated for chemerin, adiponectin, leptin, oxidized low-density lipoprotein, and C-reactive protein (CRP) levels. Results: The active T2DM patients showed significantly lower body mass index, as compared with the inactive patients. The active T2DM patients showed significantly lower levels of chemerin and CRP than those of the inactive T2DM patients (CRP lost significance after adjustment for body mass index). The active patients, compared with the inactive, presented a trend toward higher levels of adiponectin and lower values of oxidized low-density lipoprotein. Leptin differed significantly between sexes, and the active women presented a trend toward lower levels as compared with the inactive women. Conclusions: In the patients with T2DM, the practice of moderate walking in a regular basis was sufficient to reduce chemerin levels, which suggests that practice of regular physical exercise should be encouraged.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4