Study of firefly luciferin oxidation and isomerism as possible inhibition pathways for firefly bioluminescence

• Tipo: Artigo em Revista Científica Internacional
• Data: 2014

Autores

Luis Pinto da Silva (Autor) Outra; Joaquim C G E Esteves da Silva (Autor) FCUP

Revista

Título: Chemical Physics Letters

Vol. 592

Páginas: 188-191

ISSN: 0009-2614

Editora: Elsevier

Indexação

ISI Web of Knowledge - 3 Citações

Scopus - 4 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-008-ZCQ

DOI: 10.1016/j.cplett.2013.12.047

Abstract (EN): Firefly bioluminescence presents a light emitting profile with a form of a flash, due to the firefly luciferase-catalyzed formation of inhibitory products. These impair the binding of the substrate luciferin to the active site of the enzyme. However, this luciferase catalyzed pathways may not be the only ones responsible for the flash profile. The oxidation and isomerisation of the substrate luciferin lead to the formation of compounds that are also known inhibitors of firefly bioluminescence. So, the objective of this Letter was to analyze if these reactions could be capable of interfering with the bioluminescence reaction.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4