Tetracycline, oxytetracycline and chlortetracycline complexation with copper (II). Potentiometric study.

• Tipo: Artigo em Revista Científica Internacional
• Data: 2000

Autores

Couto, CMCM (Autor) Outra; Montenegro, MCBSM (Autor) FFUP; Reis, S (Autor) FFUP

Revista

Título: Quimica Nova

Vol. 23

Páginas: 457-460

ISSN: 0100-4042

Editora: Sociedade Brasileira de Quimica

Indexação

ISI Web of Knowledge - 15 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-000-ZPV

DOI: 10.1590/s0100-40422000000400005

Abstract (EN): Stability constants of complexes formed by copper (II) with three different tetracyclines (tetracycline, oxytetracycline and chlortetracycline) have been determined potentiometrically with an automatic system in aqueous medium at 25,0 +/- 0,2 degrees C and I = 0,1 mol L-1 NaNO3. The protonation constants of the three tetracyclines were also determined under the same conditions, The distribution of the complexes was then simulated at therapeutic levels of the drugs.

Idioma: Português

Tipo (Avaliação Docente): Científica

Nº de páginas: 4