Temporal Trends in Peritonitis Rates, Microbiology and Outcomes: The Major Clinical Complication of Peritoneal Dialysis

• Tipo: Artigo em Revista Científica Internacional
• Data: 2012

Autores

Ana Rocha (Autor) Outra; Anabela Rodrigues (Autor) ICBAS; Laetitia Teixeira (Autor) Outra; Maria Joao Carvalho (Autor) Outra; Denisa Mendonca (Autor) ICBAS; Antonio Cabrita (Autor) Outra

Revista

Título: Blood Purification

Vol. 33

Páginas: 284-291

ISSN: 0253-5068

Editora: Karger

Indexação

ISI Web of Knowledge - 25 Citações

Scopus - 27 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina clínica

Outras Informações

ID Authenticus: P-002-G77

DOI: 10.1159/000337377

Abstract (EN): Peritonitis remains a common complication of peritoneal dialysis (PD). The aim of this study was to analyze, in a PD center, long-term temporal trends in peritonitis rates, microbiology and outcomes. We treated 588 cases of peritonitis that occurred during 11,833.6 months at risk. Y-set and twin-bag disconnecting systems were introduced in 1990, mupirocin at the exit site in 2000 and fluconazole prophylaxis in 2005. Vancomycin and ceftazidime were the empiric protocol. Global and 5-year cohort rates were expressed as episodes/patient-year (ep/p-y). A global peritonitis rate reduction was found from 1.02 to 0.47 ep/p-y (p = 0.008). Poisson analyses performed in each of the subgroups of Gram-positive and Gram-negative peritonitis revealed no significant changes over time. No case of vancomycin resistance was identified. There was a downward trend in peritonitis-related hospitalization over time to 0.11 ep/p-y (p <= 0.001). Trend analysis showed a favorable, but changing evolution, highlighting the importance of accurate longitudinal PD center registry data and quality control. Copyright (C) 2012 S. Karger AG, Basel

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8