Vibrational Spectroscopy Studies on Biologically Relevant Molecules: From Anticancer Agents to Drugs of Abuse

• Tipo: Capítulo ou Parte de Livro
• Data: 2007

Autores

Marques, MPM (Autor) Outra; Borges, F (Autor) FFUP; Amorim da Costa, AMA (Autor) Outra; Batista de Carvalho, LAEB (Autor) Outra

Livro

Título: New Approaches in Biomedical Spectroscopy

Indexação

ISI Web of Knowledge - 1 Citação

Scopus - 2 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

CORDIS: Ciências Físicas > Química > Química aplicada

Outras Informações

ID Authenticus: P-004-E11

Abstract (EN): Vibrational spectroscopy (both Raman and Inelastic Neutron Scattering), coupled to quantum mechanical calculations, is used in order to perform a thorough analysis of several biologically relevant molecules, such as chemotherapeutic agents, biogenic polyamines and their metal chelates, cardiovascular protectors, non-steroid anti-inflammatory drugs (NSAID's), drugs of abuse and phenolic compounds. The conjugation of these techniques yields valuable information regarding the structural preferences of the systems under investigation, which may help establish the structure-activity relationships (SAR's) ruling their biological function.

Idioma: Inglês

Tipo (Avaliação Docente): Científica