Desensitization of bladder sensory fibers by intravesical capsaicin has long lasting clinical and urodynamic effects in patients with hyperactive or hypersensitive bladder dysfunction

• Tipo: Artigo em Revista Científica Internacional
• Data: 1997

Autores

Francisco Cruz (Autor) FMUP; Miguel Guimarães (Autor) Outra; Carlos Silva (Autor) FMUP; Maria Edite Rio (Autor) Outra; Coimbra A. (Autor) FMUP; Mario Reis (Autor) FMUP

Revista

Título: Journal of Urology

Vol. 157 Nº 2

Páginas: 585-589

ISSN: 0022-5347

Editora: Elsevier

Indexação

ISI Web of Knowledge - 100 Citações

Scopus - 124 Citações

Pubmed / Medline

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina clínica

CORDIS: Ciências da Saúde > Ciências Médicas > Medicina > Urologia

Outras Informações

ID Authenticus: P-001-C23

DOI: 10.1016/s0022-5347(01)65211-x

Abstract (EN): Purpose: Capsaicin was used to treat symptomatic patients with hyperactive or hypersensitive bladders. Materials and Methods: Capsaicin solution (1 mM.) was instilled into the bladder of 16 patients with spinal hyperreflexia, bladder instability or hypersensibility. Results: Frequency decreased in 14 patients and continence was achieved in 10 of 14 incontinent cases. Mean first desire to void and maximal cystometric capacity increased significantly. These effects lasted for 6 to 12 months and were renewed following repeat treatment. Conclusions: Bladder afferent desensitization with capsaicin is promising in patients with motor or sensory bladder dysfunction, although initial pungency might limit its use.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5