Association of trace element status in COVID-19 patients with disease severity

• Tipo: Artigo em Revista Científica Internacional
• Data: 2022

Autores

Bego, T (Autor) Outra; Meseldzic, N (Autor) Outra; Prnjavorac, B (Autor) Outra; Prnjavorac, L (Autor) Outra; Marjanovic, D (Autor) Outra; Azevedo, R (Autor) Outra; Pinto, E (Autor) Outra; Duro, M (Autor) Outra; Couto, C (Autor) Outra; Agostinho Almeida (Autor) FFUP

Revista

Título: Journal of Trace Elements in Medicine and Biology

Vol. 74

ISSN: 0946-672X

Editora: Elsevier

Indexação

ISI Web of Knowledge - 2 Citações

Scopus - 2 Citações

Outras Informações

ID Authenticus: P-00X-2RW

DOI: 10.1016/j.jtemb.2022.127055

Abstract (EN): Caused by the new SARS-CoV-2 coronavirus, COVID-19 (coronavirus disease 2019) evolves with clinical symptoms that vary widely in severity, from mild symptoms to critical conditions, which can even result in the patient's death. A critical aspect related to an individual response to SARS-CoV-2 infection is the competence of the immune system, and it is well known that several trace elements are essential for an adequate immune response and have anti-inflammatory and antioxidant properties that are of particular importance in fighting infection. Thus, it is widely accepted that adequate trace element status can reduce the risk of SARS-CoV-2 infection and disease severity. In this study, we evaluated the serum levels of Cu, Zn, Se, Fe, I and Mg in pa-tients (n = 210) with clinical conditions of different severity ( mild , moderate , severe and exitus letalis , i. e., patients who eventually died). The results showed significant differences between the four groups for Cu, Zn, Se and Fe, in particular a significant trend of Zn and Se serum levels to be decreased and Cu to be increased with the severity of symptoms. For Mg and I, no differences were observed, but I levels were shown to be increased in all groups.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9