Multiple model adaptive control of neuromuscular blockade: Design guidelines and clinical cases

• Type: Article in International Conference Proceedings Book
• Date: 2007

Authors

Teresa Mendonça (Author) FCUP; Hugo Magalhães (Author) Other; João M. Lemos (Author) Other; Paula Rocha (Author) FEUP; Simão Esteves (Author) Other

Conference proceedings International

Title: 2007 European Control Conference, ECC 2007

Pages: 2541-2546

2007 9th European Control Conference, ECC 2007

2 July 2007 through 5 July 2007

Indexing

ISI Web of Knowledge

Scopus - 5 Citations

INSPEC

Other information

Authenticus ID: P-00A-BYA

Abstract (EN): The high level of uncertainty of the dynamic response of patients subject to anaesthesia motivates the use of adaptive control methods. This paper proposes an approach based on Switched Multiple Model Adaptive Control (SMMAC) to tackle this problem in what concerns the control of the neuromuscular blockade level. It is shown how to design the different elements of the SMMAC controller, enhancing the importance of the observer polynomial, that is shown to be instrumental to stabilize the loop. Clinical results using atracurium as blocking agent are reported, thereby illustrating the application of the proposed approach in actual clinical practice.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6