Bioinorganic Chemistry
| Code: | Q2017 | Acronym: | Q2017 | Level: | 200 |
| Keywords | |
|---|---|
| Classification | Keyword |
| OFICIAL | Chemistry |
Instance: 2020/2021 - 2S 
| Active? | Yes |
| Responsible unit: | Department of Chemistry and Biochemistry |
| Course/CS Responsible: | Bachelor in Biochemistry |
Cycles of Study/Courses
| Acronym | No. of Students | Study Plan | Curricular Years | Credits UCN | Credits ECTS | Contact hours | Total Time |
|---|---|---|---|---|---|---|---|
| L:BQ | 98 | Official Study Plan | 2 | - | 6 | 56 | 162 |
Fields changed: Objectives, Resultados de aprendizagem e competências, Métodos de ensino e atividades de aprendizagem, Fórmula de cálculo da classificação final, Bibliografia Complementar, Melhoria de classificação, Obtenção de frequência, Programa, Bibliografia Obrigatória, Avaliação especial
Teaching language
PortugueseObjectives
Understand the role of metal ions in biological systems at a molecular level and the basic chemical principles that promote their reactivity. During classes exemples will be given of the importance of bioinorganic chemistry in several fields (pharmacology, medicine, agriculture, metallurgy, veterinary, among others) .
Learning outcomes and competences
Understand the role of metal ions in biological systems, based on their chemical properties.
Working method
PresencialProgram
Lectures:
1.The thermodynamics of complex es formation
2.Geometric, spectroscopic and magnetic properties of metai ion complexes
3.Mechanisms of reactions of transition metal compounds
4.Bioinorganic Chemistry - general aspects. Coordination sites of metal cations in biological systems.
5. Metals at the Center of Photosynthesis: Magnesium and Manganese
6. The Dioxygen Molecule, O2: Uptake, Transport and Storage of an Inorganic Natural Product
7. Catalysis through Hemoproteins: Electron Transfer, Oxygen Activation and Metabolism of Inorganic Intermediates
8. Iron–Sulfur and Other Non-heme Iron Proteins
9. Uptake, Transport and Storage of an Essential Element, as Exemplified by Iron
10. Copper-containing Proteins: An Alternative to Biological Iron
11. Zinc: Structural and Gene-regulatory Functions and the Enzymatic Catalysis of
Hydrolysis and Condensation Reactions
Practical classes:
Case studies that will developed the contents of the lectures; laboratory classes: the aim of the laboratory classes is to integrate concepts from biology and inorganic chemistry by performing experiments that lie at the interface of these two subjects. Lecture topics will be reinforced through experiments covering synthesis and analysis of bioinorganic model compounds, enzyme activity as it relates to metal availability, and metal therapeutics.
Mandatory literature
Cris J. Jones; d- and f- Block Chemistry, 2002. ISBN: 0-47 1-22476-6Wolfgang Kaim, Brigitte Schwederski, Axel Klein; Bioinorganic Chemistry:Inorganic elements in the chemistry of life, WILEY, 2013
Complementary Bibliography
Dieter Rehder; Bioinorganic Chemistry, Oxford, 2014. ISBN: 978-0-19-965519-9Robert R, Crichton, Ricardo Louro (Eds-); Practical approaches to biological inorganic chemistry, Elsevier, 2013
Robert R. Crichton; Biological Inorganic Chemistry, Elsevier, 2012. ISBN: 978-0-444-53782-9
Rosette M.Roat-Malone; Bioinorganic Chemistry- a short course, John Wiley & Sons , 2002
Teaching methods and learning activities
In theoretical-practical classes students are invited to solve and report some case studies. At the end of the Laboratory classes students have to make a 20 minutes oral presentation using multimedia resources, followed by a discussion of 10 minutes.
Evaluation Type
Distributed evaluation with final examAssessment Components
| designation | Weight (%) |
|---|---|
| Exame | 70,00 |
| Trabalho laboratorial | 30,00 |
| Total: | 100,00 |
Amount of time allocated to each course unit
| designation | Time (hours) |
|---|---|
| Estudo autónomo | 106,00 |
| Frequência das aulas | 28,00 |
| Trabalho laboratorial | 28,00 |
| Total: | 162,00 |
Eligibility for exams
Admission to the final exam is only possible for those students that have not missed more than 1/4 of the number of the planned practical classes, have positive grade on at least 2/3 of the practical lab work and that have a final practical classification higher than 9.5.Calculation formula of final grade
N = 0,30×P + 0,70×NT.
P is calculated as the weighted average of the classifications obtained in the laboratory classes (0,70×R + 0,30×AO).
NT = (T1+T2+T3)/3
In appeal time exam the student will carry out a comprehensive examination (all matter) and the classification obtained is NT.
Special assessment (TE, DA, ...)
Working students, if they wish not to carry out continuous assessment, may opt for a global exam in the normal time, in which case their theoretical final grade (NT) is equal to the grade obtained in this global exam.In this case, they must timely notify, before the first test, the UC regent.
If these students can not attend the practical component, they must perform a final laboratory examination, on a date to be agreed with the UC regent.
Classification improvement
All students who wish to make grade improvement (a GLOBAL EXAM on the subject taught) after having passed the UC have to register for it in Academic Services.Page created on: 2024-11-09 at 06:50:55 | Acceptable Use Policy | Data Protection Policy | Complaint Portal