Organic Chemistry II

Code:

Q273

Acronym:

Q273

Keywords
Classification	Keyword
OFICIAL	Chemistry

Instance: 2015/2016 - 1S

Active?	Yes
Responsible unit:	Department of Chemistry and Biochemistry
Course/CS Responsible:	Bachelor in Biochemistry

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
L:BQ	123	Plano de Estudos a partir de 2007	2	-	5	-

Teaching language

Portuguese

Objectives

The main objective of this course is to provide the students with the appropriate skills to solve practical problems in contemporary organic chemistry, by understanding the connection between structure and function. After learning the structures and functions of the various families of organic compounds, the mechanisms of new important reactions will be discussed. During this course, new applications of organic chemistry in the life sciences, industrial practices, environmental monitoring and clean-up as far as synthesis and green chemistry will be referred to.

Learning outcomes and competences

By the end of this course the students should know the important reactions of a range of functional groups, should understand the major classes of reaction mechanisms and should deal with the basic techniques of synthetic organic chemistry (isolation, purification, identification, and design and work-up of reactions)

Working method

Presencial

Pre-requirements (prior knowledge) and co-requirements (common knowledge)

RECOMMENDED PRE-REQUISITES It is recommended that the students previously attend the following courses: 1 Fundamentos de Química 2 Laboratório de Química 3 Química Orgânica I 4 Estrutura e Reactividade em Química Inorgânica

 

Program

Lectures

Chapter 1 – Aldehydes and ketones: the carbonyl group
Chapter 2 – Carbohydrates: polyfunctional compounds in Nature
Chapter 3 – Amino acids, peptides, proteins and nucleic acids: nitrogen-containing polymers in Nature
Chapter 4 – Alkynes: the carbon-carbon triple bond
Chapter 5 – Delocalized pi systems
Chapter 6 – Benzene and aromaticity: electrophilic aromatic substitution
Chapter 7 – Electrophilic attack on derivatives of benzene: substituents control regioselectivity
Chapter 8 – Enols, enolates and the aldol condensation: ,-unsaturated aldehydes and ketones
Chapter 9 – Carboxylic acids
Chapter 10 – Carboxylic acid derivatives

Practical classes

- Purification of solid organic compounds by crystallization: choice of solvent to the crystallization of an unknown substance. Benzoic acid crystallization
- Thin-layer chromatographic analysis of various analgesics
- Separation of an organic mixture’s components by liquid-liquid extraction
- Aldol condensation: reaction of benzaldehyde and acetone
- Acid-catalyzed esterification: synthesis of D-glucose penta-acetate
- Unimolecular nucleophilic  substitution: synthesis of tert-butyl chloride

Mandatory literature

000073485. ISBN: 0-7167-4374-4
000075516. ISBN: 85-363-0413-8
000071896. ISBN: 0-7167-2721-8

Teaching methods and learning activities

1 - Lectures
2 hours per week

The different subjects will be presented by using multimedia tools.  The slides will be available in the web page of the discipline, as well as complimentary documents.

2- Practical sessions
Practical classes (2 hours per week, compulsory classes)

The students will form groups (2 to 3 students per group) and will work in group.
The students will perform some fundamental laboratory experiments in Organic Chemistry that include synthesis, purification and analysis of organic compounds.

keywords

Physical sciences > Chemistry > Organic chemistry

Evaluation Type

Distributed evaluation with final exam

Assessment Components

designation	Weight (%)
Exame	75,00
Trabalho laboratorial	25,00
Total:	100,00

Eligibility for exams

The students cannot miss more than 1/4 of the number of practical sessions on a basis of 12 weeks. The maximum absences are 3.

Calculation formula of final grade

Students with a final classification (N) equal to or higher than 9,5(20) will pass.

The final grade is calculated as a weighted average of the pratical evaluation (P) and theoretical evaluation (T):

N = 0,25 x P + 0,75 x T

P is calculated as the average of the classifications obtained in the laboratory classes.
The practical classification is calculated by the following formula:

P = 0,7 x IP + 0,3 RR

where IP is the practical assessment made by the teaching staff and RR is the mark attained in the written reports.

T is the weighted average of the tests (T1 and T2) or the final exam classification. Students with an weighted average of the tests lower than 9,5 must do the final exam.

Dates of tests: T1 -  November 4th (Monday), 17-19 h

                         T2 - Exam's first date

Examinations or Special Assignments

Working students may, in the case where they did not attend the practical sessions, request a practical exam whose mark will replace the practical mark.

Classification improvement

Mark-improvement can be attained doing both tests or the final exam.

Observations

RECOMMENDED PRE-REQUISITES It is recommended that the students previously attend the following courses: 1 Fundamentos de Química 2 Laboratório de Química 3 Química Orgânica I 4 Estrutura e Reactividade em Química Inorgânica