The development and optimization of a modified single-drop microextraction method for organochlorine pesticides determination by gas chromatography-tandem mass spectrometry

• Type: Article in International Scientific Journal
• Date: 2012

Authors

Virginia C Fernandes (Author) Other; Viswanathan Subramanian (Author) Other; Nuno Mateus (Author) FCUP; Valentina F Domingues (Author) Other; Cristina Delerue Matos (Author) Other

Journal

Title: Mikrochimica Acta

Vol. 178

Pages: 195-202

ISSN: 0026-3672

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 34 Citations

Scopus - 37 Citations

Scientific classification

FOS: Natural sciences > Chemical sciences

Other information

Authenticus ID: P-002-8M2

DOI: 10.1007/s00604-012-0810-9

Abstract (EN): We have developed a new method for single-drop microextraction (SDME) for the preconcentration of organochlorine pesticides (OCP) from complex matrices. It is based on the use of a silicone ring at the tip of the syringe. A 5 mu L drop of n-hexane is applied to an aqueous extract containing the OCP and found to be adequate to preconcentrate the OCPs prior to analysis by GC in combination with tandem mass spectrometry. Fourteen OCP were determined using this technique in combination with programmable temperature vaporization. It is shown to have many advantages over traditional split/splitless injection. The effects of kind of organic solvent, exposure time, agitation and organic drop volume were optimized. Relative recoveries range from 59 to 117 %, with repeatabilities of < 15 % (coefficient of variation) were achieved. The limits of detection range from 0.002 to 0.150 mu g kg(-1). The method was applied to the preconcentration of OCPs in fresh strawberry, strawberry jam, and soil.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8