Thermodynamic Modeling of Several Aqueous Alkanol Solutions Containing Amino Acids with the Perturbed-Chain Statistical Associated Fluid Theory Equation of State

• Type: Article in International Scientific Journal
• Date: 2009

Authors

Luísa A. Ferreira (Author) FEUP; Martin P. Breil (Author) Other; Simão P. Pinho (Author) FEUP; Eugénia A. Macedo (Author) FEUP; Jorgen M. Mollerup (Author) Other

Journal

Title: Industrial & Engineering Chemistry Research

Vol. 48

Pages: 5498-5505

ISSN: 0888-5885

Publisher: American Chemical Society

Indexing

ISI Web of Knowledge - 14 Citations

ISI Web of Science

Scopus - 15 Citations

COMPENDEX

Scientific classification

FOS: Engineering and technology > Chemical engineering

Other information

Authenticus ID: P-003-J96

DOI: 10.1021/ie801567w

Abstract (EN): The perturbed-chain statistical associated fluid theory EoS was applied to model the solubilities of glycine, DL-alanine, L-serine, L-threonine, and L-isoleucine in pure water, pure alcohols (ethanol, I-propanol, and 2-propanol) and in mixed solvent systems. Three pure component nonassociating parameters for the amino acids were fitted to the densities, activity and osmotic coefficients, vapor pressures, and water activity of their aqueous solutions. The solubilities of amino acids in pure and mixed solvent systems were calculated on the basis of the phase equilibrium conditions for a pure solid and a fluid phase. The hypothetical melting properties of each amino acid were fitted, to accurately correlate the solubilities in pure water. Only one temperature independent binary parameter is required for each amino acid/solvent pair. The model can accurately describe the solubility of the amino acids in water, but the correlation for the solubility in pure alcohols was not so satisfactory. The solubility in mixed solvents (ternary systems) was predicted on the basis of the modeling of the solubility in pure solvents, without any additional fitting of the parameters, and the results achieved were reasonable. Fitting the binary parameter for the pair amino acid/alcohol not to the solubility in pure alcohol, but to the solubility in the mixed solvent system, the description of the solubility in the mixed solvent systems was clearly improved and the results were in fair agreement with the experimental data for all mixture compositions. The results showed a global root-mean-square deviation in mole fraction of 0.0032 for correlation and 0.0070 for prediction.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8