Semi-automatic Method of Stent Development for Hemodynamic Simulations in Patient Coronary Arteries with Disease

• Type: Chapter or Part of a Book
• Date: 2022-05

Authors

L. Matias (Author) Other; C.F. Castro (Author) FEUP; C.C. António (Author) FEUP; L.C. Sousa (Author) FEUP; S.I.S. Pinto (Author) FEUP

Book

Title: Theoretical Analyses, Computations, and Experiments of Multiscale Materials, Advanced Structured Materials

Pages: 443-458

ISBN: 978-3-031-04548-6

Indexing

Scopus

Scientific classification

CORDIS: Technological sciences > Engineering > Mechanical engineering

FOS: Engineering and technology > Mechanical engineering ; Engineering and technology > Medical engineering

Other information

Authenticus ID: P-00W-J9V

DOI: 10.1007/978-3-031-04548-6_21

Abstract (EN): Atherosclerosis contributes to the development cardiovascular diseases, the leading cause of death in the world. Complications arising from atherosclerosis, such as stenosis (an abnormal narrowing of a blood vessel, which can lead to its clogging) exacerbate the risk of cardiovascular disorders. Besides aging, sedentary lifestyle, unhealthy diet and tobacco consumption are among the risk factors which increase the likelihood of developing atherosclerosis overtime. One way to prevent stenosis development, due to atherosclerosis, is by inserting stents inside the relevant blood vessels. Stents are small metal tubes which can be expanded to keep the passageway open and improve blood flow, essentially resulting in an arterioplasty. The achievement of an accurate stent, such as accurate mesh, length and other features, specific for a patient coronary artery with atherosclerosis, is still a challenge in clinical practice. Therefore, after developing numerical based coding solution that simulate hemodynamic conditions as close as possible to reality, the goal of the present work is to develop a semi-automatic method to create a stent in the stenotic location of patient-specific coronary arteries. As far aswe know, no authors have been able to quickly and effectively place the stent in a model of a patient¿s artery, which is subject to the complex geometry of the coronary such as curvature, tortuosity, etc. The impact of stent length was considered, in order to verify which is the ideal, for a patient case, avoiding restenosis occurrence. After hemodynamic simulations in the model artery with stenosis and in the model artery with stent, it is observed that strong atherosusceptible regions just after the stenosis are eliminated after stent insertion. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Language: English

Type (Professor's evaluation): Scientific

Notes: I. Giorgio, L. Placidi, E. Barchiesi, B.E. Abali, H. Altenbach (eds.), Theoretical Analyses, Computations, and Experiments of Multiscale Materials, Advanced Structured Materials, 175, Chapter 21, pp.443-458, Springer, Cham, 2022.

No. of pages: 16