In vitro biodegradability of chitosan-organosiloxane hybrid membrane

• Type: Article in International Scientific Journal
• Date: 2005

Authors

Tsuru, K (Author) Other; Shirosaki, Y (Author) Other; Hayakawa, S (Author) Other; Osaka, A (Author) Other; Lopes, MA (Author) FEUP; Santos, JD (Author) FEUP; Fernandes MH (Author) FMDUP

Journal

The Journal is awaiting validation by the Administrative Services.

Title: BIOCERAMICS, VOL 17

Vol. 14

Pages: 823-826

Indexing

ISI Web of Knowledge - 3 Citations

ISI Web of Science

Scopus - 5 Citations

Scientific classification

FOS: Engineering and technology > Materials engineering

Other information

Authenticus ID: P-000-58M

Abstract (EN): Chitosan-silicate hybrid membranes were prepared using gamma-glycidoxypropyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and Si-29 cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4