Determination of salivary cotinine as tobacco smoking biomarker

• Type: Another Publication in an International Scientific Journal
• Date: 2018

Authors

Ramdzan, AN (Author) Other; Almeida, MIGS (Author) Other; McCullough, MJ (Author) Other; Marcela A Segundo (Author) FFUP; Kolev, SD (Author) Other

Journal

Title: TrAC - Trends in Analytical Chemistry

Vol. 105

Pages: 89-97

ISSN: 0165-9936

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 9 Citations

Other information

Authenticus ID: P-00P-DFY

DOI: 10.1016/j.trac.2018.04.015

Abstract (EN): Cotinine, the first metabolite of nicotine, is often used as a biomarker in the monitoring of environmental tobacco smoke (ETS) exposure due to its longer half-life. The use of saliva to measure the concentration of cotinine is an attractive alternative to conventional biological matrices (such as blood and urine) due to its simple and non-invasive collection method. However, the detection of minute concentrations of cotinine in saliva poses a significant challenge. This review critically assesses the advantages and disadvantages of the most frequently used sample pre-treatment and detection methods for the analysis of salivary cotinine.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9