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Publication

The triad psoriasis-obesity-adipokine profile

Title
The triad psoriasis-obesity-adipokine profile
Type
Another Publication in an International Scientific Journal
Year
2016
Authors
Coimbra, S
(Author)
Other
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Cristina Catarino
(Author)
FFUP
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Alice Santos Silva
(Author)
FFUP
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Journal
Vol. 30
Pages: 1876-1885
ISSN: 0926-9959
Publisher: Wiley-Blackwell
Other information
Authenticus ID: P-00M-78P
Abstract (EN): Psoriasis is a chronic inflammatory skin disease, often associated with overweight/obesity. The adipose tissue is a complex organ that secretes several adipokines, involved in the regulation of some metabolic processes, such as lipid metabolism, glucose homeostasis, angiogenesis, blood pressure and inflammation. In obesity, the distribution and function of adipose tissue, and the adipokine profile are altered. The unbalanced production of pro- and anti-inflammatory adipokines in obesity, contributes to the development of a chronic low-grade inflammation state, which seems to favour worsening of psoriasis lesion and a poorer response to treatment. In this review, we will debate published data concerning the current knowledge about the triad psoriasis-obesity-adipokine profile.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 10
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