Abstract (EN):
The vast majority of modern technologies used to separate and purify (remove) particles or
other substances from a fluid media are very limited in what concerns their ability to selectively
separate and purify several substances at the same step and in the same device. There is a
clear need to develop such processing techniques that may allow us to work continuously and if
well developed will represent a major tool in many areas of science, especially in what concerns
biomedicalapplications, ranging from diagnostics until treatment of diseases.
Besides the obvious economical advantage, such processes would also potentiate new applications
that are being halted by the inefficiency of such processing purifications, as they presently
require at least some kind of cascade procedure (in the best case) that becomes impractical after
one or two steps.
Magnetic separation is a classical technique that may be applied nowadays to separate and
purify potentially any substance, when allied to magnetic tagging and carrier technologies. However
it also has the same limitation to selectively separate only one particle/substance at each step. In
order to overcome this limitation, we have been developing in the last decade an area which is
denominated as magnetic classification. Magnetic classification is potentially capable of selectively
separating substances (either containing relevant magnetic characteristics, either being previously
tagged with particles that possess these magnetic properties) from each other using only one single
step and one machine.
The research on magnetic classification so far has been very limited, mainly due to lack of
funding, some bureaucratic problems, to the development of only limited applications, and because
it is still a new technique and thus it is still in an embryonic state.
Concerning all the previous issues, we have developed recently a proof the concept anfundamentals
of magnetic classification, in such a way that we were able to show its feasibility and
specially to determine the influence of some the force balances and some of the main parameters
in biological and biomedical media. Based on the preliminary results we are now ready to develop,
design and control a larger scale device for future applications.
Language:
English
Type (Professor's evaluation):
Scientific