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FC6 - Departamento de Ciência de Computadores FC5 - Edifício Central FC4 - Departamento de Biologia FC3 - Departamento de Física e Astronomia e Departamento GAOT FC2 - Departamento de Química e Bioquímica FC1 - Departamento de Matemática

Courses

Master in Applications in Biotechnology and Synthetic Biology

General information

Official Code: MA44
Acronym: M:ABBS
Description: O M:ABBS centra-se em promover a compreensão das várias dimensões relevantes em biotecnologia e biologia sintética e suas diversas áreas de aplicação científica e tecnológica, com vista a fazer face aos atuais desafios societais e a promover uma maior sustentabilidade. Assim, este ciclo de estudos confere conhecimento prático e teórico no âmbito da aplicação de conceitos fundamentais da química e da biologia para explicar e descrever processos fundamentais em biotecnologia e biologia sintética, visando integrar os conhecimentos adquiridos numa perspetiva global das aplicações da química e da biologia nos mais diversos quadrantes de intervenção da biotecnologia. Visa-se, também: conferir aptidões laboratoriais básicas em biotecnologia e biologia sintética; promover a comunicação e colaboração eficiente em equipa; preparar para a elaboração e apresentação de comunicações científico-tecnológicas adaptadas às especificidades de cada audiência; treinar as capacidades de organização de tare

Certificates

  • Master's degree in Applications in Biotechnology and Synthetic Biology (120 ECTS credits)
  • Specialization in Applications in Biotechnology and Synthetic Biology (60 ECTS credits)

Courses Units

Bionanotechnology

Q4087 - ECTS This course focus in the basics of bionanotechnology and current applications of bionanotechnology.

Industrial Biochemistry

Q4085 - ECTS

 

The aim of this lecture is to approach several fields of Biochemistry, Biotechnology, Cellular and Molecular Biology, Biophysics, Biology, Chemistry and Bioengineering in an industrial context. Several processes involved in the industry will be assessed (namely bioprocesses), as well as the role of Biotechnology in the environment and in health.

 

  Practical classes include 5 practical works.

Whenever possible, the content of the practical classes will be in articulation with the theoretical classes.

Seed Biotechnology

BIOL4050 - ECTS Provide current knowledge about seed biotechnology and the type of research that can be done to produce future seed industry leaders. It is intended that students master the biology of seeds; Structure, physiology and genetics so as to be able to present cutting-edge research projects in sustainable agriculture, biotechnology, crop use and molecular biology.

Cell Cultures I - Plants

BIOL4059 - ECTS

Provide students with basic knowledge of in vitro plant cell cultures and practical applications. Provide students with basic knowledge of manipulation in aseptic conditions.

Cell cultures II - Animals

BIOL4060 - ECTS

Provide students with basic knowledge of in vitro animal cell cultures, practical applications and cryopreservation techniques. Provide students with basic knowledge of cellular manipulation in aseptic conditions.

Laboratory of Microbiology

BIOL4061 - ECTS

Bibliography search and organization of a database.

Discussion of scientific papers.

Improve knowledge on microbiological techniques used commonly in nowadays research.

Develop capacities to conceive structure and put in place an experimental work/design.

Organization of results obtained in the experimental work, elaboration of a poster as for presentation in a scientific meeting.

Elaboration of a manuscript.

DNA Manipulation and Synthetic Biology

BIOL4055 - ECTS


Provide the basic concepts and terminology related to Synthetic Biology, and advanced concepts on DNA manipulation and recombinant DNA technologies using a synthetic biology approach. Familiarization with the design of synthetic modules and circuits and use of bioinformatics tools for codon optimization and in silico construction. Understand how the expression of heterologous proteins can be modulated, using for example different regulatory elements. Familiarization with the analysis of original scientific articles, logic of experimental design  and data analysis. Training in oral and written communication.

 

Advanced Methods for Structural and Morphological Analysis

Q4084 - ECTS

- Recognize the role of structural and morphological analysis methods in a wide range of applications, from Pure and Applied Chemistry or (Nano)Materials Science to Biomedicine

- Learn the most relevant morphological and structural analysis techniques and their adequacy according to the desired applications

- Identify the scope and limitations that characterize each of the relevant structural analysis methods

- Identify the most appropriate techniques for the morphologial and structural characterization of different compounds and materials

- Read/interpret scientific papers related to the course area

- Elaborate a monograph on a selected subject related to the course area

- Present an oral communication on a relevant topic related to the course area

 

Food Microbiology: From Preservation to Safety

BIOL4086 - ECTS The course should grant the students with the knowledge needed to understand the importance of food microbiology and its applications in Food Science and Technology, particularly the interactions between microorganisms and food within a food safety perspective.

The contents of this course are organized in order to enable students to understand the importance of microorganisms as etiological agents of disease, as agents of spoilage, and as agents of production and/or preservation of food.

The laboratory program aims to familiarize students with the main methodologies and microbiological criteria used in microbiological analysis of water, food products, surfaces and food handlers.

Biological Models

BIOL4056 - ECTS This UC meets the current needs of using biological models in research and in biotechnology / synthetic biology. It will provide the students with the basic knowledge necessary to select suitable models to adress specific research questions and the knowledge to utilize and manipulate these models.

Synthesis of Bioproducts

Q4082 - ECTS

The course “Synthesis of Bioproducts” will focus on major chemical strategies towards the synthesis of biologically relevant molecules, mainly peptides, oligonucleotides, and peptide-nucleic acids (PNA), as well as chemoselective ("click") strategies for the production of bioconjugates. Different areas of application of the synthetic strategies addressed will be equally presented.

A hybrid teaching model will be applied, combining (i) lectures to introduce the fundamental concepts and reaction mechanisms relevant for each topic, and present selected case-studies (presential or e-learning) and (ii) experimental projects (in the laboratory) aimed at the chemical syntheis of a given target bioproduct, fostering the "learning by doing" paradigm.

Systems for Transport and Intracellular Delivery

Q4083 - ECTS

The present course aims to provide students with a comprehensive view of the of existing intracellular delivery systems, their properties and how they can be modulated according to the desired biomedical and biotechnological applications. 

Molecular Bioinformatics I

Q4088 - ECTS

We intend to provide students with a comprehensive overview of current Molecular Bioinformatics topics.
In practical labs, students are encouraged to develop small protocols on the research topics covered.

Molecular Bioinformatics II

Q4089 - ECTS

We intend to provide students with a comprehensive overview of current Molecular Bioinformatics topics.
In practical labs, students are encouraged to develop small protocols on the research topics covered.

Systems Biology and Bioprocesses

BIOL4057 - ECTS Basic conccepts of System's Biology and Bioprocesses will be presented and discussed, trying as much as possible to frame them within appropriate case studies.The competences aquired will form  the basis for future work in research and development labs, as well as in industrial environements, forming important basis for future insertion in different labou market areas (food industry, pharmaceutical, cosmetics).

Environmental Biotechnology

BIOL4062 - ECTS

Blue Biotechnology

BIOL4064 - ECTS (i) The program is prepared to provide advanced theoretical and practical knowledge in Marine Biotechnology; (ii) to provide knowledge on the relevance of genetic diversity, (iii) genomic analyzes in Blue Biotechnology; (iv) to provide a knowledge basis on the diverse methodologies of biomass production, extraction and isolation of new compounds, (v) analysis of the bioactivity of marine natural products, its structural elucidation and (vi) economic valorization;

Project Management

BIOL4107 - ECTS

The UC aims to develop in the students skills in the creation of new business ventures in the area of life sciences, integrating both a theoretical and a strong practical component. The presentation and discussion of concepts and methodologies, will aim to validate the application of the market potential of a concrete business project in the area of biosciences.

At the end of the course, students should:

1 Understanding the challenges of the creation, validation and start-up of new business process projects;

  1. Knowing the different functional areas of management and how they interrelate in the definition of a startup technology-based strategy.
  2. Able to apply a set of concepts, methods and management tools for the analysis, discussion and implementation of knowledge-intensive business projects in the area of life sciences.
  3. Able to develop teamwork.

Nanochemistry

Q4090 - ECTS

- To identify the role of Chemistry in the context of Nanosciences and Nanotechnology.

- To gain knowledge in methods of production of nanomaterials and characterization techniques for nanomaterials analysis.

- To select the most appropriate experimental techniques for the characterization of each nanomaterial.

- To identify the technological applications of each type of nanomaterial.

- To identify potential risks, regulations, and ethical issues associated with the impact of the production and commercialization of nanotechnology-based products on society.

- To read and interpret critically scientific papers in the areas of Nanosciences and Nanotechnology.


 

Functional Omics

BIOL4068 - ECTS This UC meets the latest tools in the study of biotechnology and synthetic biology. It gives the student a transversal and integrative view of how to study different degrees of organization of the cell /organism. At the end of this course the student will:
• Understand the fundamentals of the main methods used in each omic (genomic/ transcritomic /metabolomics and cytomic) and the respective methodologies and instrumental bases of analysis.
• Know methodologies associated to the acquisition of multiparametric data and bioinformatics based tools associated with the different levels of omics, and how to work with software commonly used in its analysis.
• Recognize the potential of integrating these data / omics datasets into biological inference strategies
• Understand, for each level, potential applications in biology, biotechnology and synthetic biology
• Develop independent thinking in experimental design using omics tools especially in these areas

Dissertation

BIOL/Q5000 - ECTS To get the MSc. Degree, the student will have to present a Dissertation or an Internship Report, depending on whether he/she has chosen to engage into an academic-scientific dissertation or into an internship in a company. Each student should attain the specific goals of his/her specific Project.

Internship

BIOL/Q5001 - ECTS To get the MSc. Degree, the student will have to present a Dissertation or an Internship Report, depending on whether he/she has chosen to engage into an academic-scientific dissertation or into an internship in a company. Each student should attain the specific goals of his/her specific Project.

Molecular Regulation of Gene Expression

BIOL4058 - ECTS The overall objective of this course is to give students a deeper understanding of how the regulation of plant gene expression occurs, including all molecular events arising from the regulation of promoter activity to mRNA translation, via regulation of mRNA stability and duration and all the cellular events that underlie it (splicings, regulation by interference RNA (RNAi) and the various cytoplasmic mechanisms of post-transcriptional control). As competencies and learning outcomes, it is intended that students become able to understand the molecular mechanisms underlying the production, maintenance and efficiency of translation of mRNAs, thus becoming aware of the needs, care and strategies to take under various procedures as for example, the production of genetically modified plants, or analysis of accumulation of transcripts and/or their encoded products.
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