Official Code: | MA44 |
Acronym: | M:ABBS |
Description: | O M:ABBS centra-se em promover a compreensão das várias dimensões relevantes em biotecnologia e biologia sintética e suas diversas áreas de aplicação científica e tecnológica, com vista a fazer face aos atuais desafios societais e a promover uma maior sustentabilidade. Assim, este ciclo de estudos confere conhecimento prático e teórico no âmbito da aplicação de conceitos fundamentais da química e da biologia para explicar e descrever processos fundamentais em biotecnologia e biologia sintética, visando integrar os conhecimentos adquiridos numa perspetiva global das aplicações da química e da biologia nos mais diversos quadrantes de intervenção da biotecnologia. Visa-se, também: conferir aptidões laboratoriais básicas em biotecnologia e biologia sintética; promover a comunicação e colaboração eficiente em equipa; preparar para a elaboração e apresentação de comunicações científico-tecnológicas adaptadas às especificidades de cada audiência; treinar as capacidades de organização de tare |
The aim of this lecture is to approach several fields of Biochemistry, Biotechnology, Cellular and Molecular Biology, Biophysics, Biology, Chemistry and Bioengineering in an industrial context. Several processes involved in the industry will be assessed (namely bioprocesses), as well as the role of Biotechnology in the environment and in health.
Practical classes include 5 practical works.
Whenever possible, the content of the practical classes will be in articulation with the theoretical classes.
Provide students with basic knowledge of in vitro plant cell cultures and practical applications. Provide students with basic knowledge of manipulation in aseptic conditions.
Provide students with basic knowledge of in vitro animal cell cultures, practical applications and cryopreservation techniques. Provide students with basic knowledge of cellular manipulation in aseptic conditions.
Bibliography search and organization of a database.
Discussion of scientific papers.
Improve knowledge on microbiological techniques used commonly in nowadays research.
Develop capacities to conceive structure and put in place an experimental work/design.
Organization of results obtained in the experimental work, elaboration of a poster as for presentation in a scientific meeting.
Elaboration of a manuscript.
Provide the basic concepts and terminology related to Synthetic Biology, and advanced concepts on DNA manipulation and recombinant DNA technologies using a synthetic biology approach. Familiarization with the design of synthetic modules and circuits and use of bioinformatics tools for codon optimization and in silico construction. Understand how the expression of heterologous proteins can be modulated, using for example different regulatory elements. Familiarization with the analysis of original scientific articles, logic of experimental design and data analysis. Training in oral and written communication.
- Recognize the role of structural and morphological analysis methods in a wide range of applications, from Pure and Applied Chemistry or (Nano)Materials Science to Biomedicine
- Learn the most relevant morphological and structural analysis techniques and their adequacy according to the desired applications
- Identify the scope and limitations that characterize each of the relevant structural analysis methods
- Identify the most appropriate techniques for the morphologial and structural characterization of different compounds and materials
- Read/interpret scientific papers related to the course area
- Elaborate a monograph on a selected subject related to the course area
- Present an oral communication on a relevant topic related to the course area
The contents of this course are organized in order to enable students to understand the importance of microorganisms as etiological agents of disease, as agents of spoilage, and as agents of production and/or preservation of food.
The laboratory program aims to familiarize students with the main methodologies and microbiological criteria used in microbiological analysis of water, food products, surfaces and food handlers.
The course “Synthesis of Bioproducts” will focus on major chemical strategies towards the synthesis of biologically relevant molecules, mainly peptides, oligonucleotides, and peptide-nucleic acids (PNA), as well as chemoselective ("click") strategies for the production of bioconjugates. Different areas of application of the synthetic strategies addressed will be equally presented.
A hybrid teaching model will be applied, combining (i) lectures to introduce the fundamental concepts and reaction mechanisms relevant for each topic, and present selected case-studies (presential or e-learning) and (ii) experimental projects (in the laboratory) aimed at the chemical syntheis of a given target bioproduct, fostering the "learning by doing" paradigm.
The present course aims to provide students with a comprehensive view of the of existing intracellular delivery systems, their properties and how they can be modulated according to the desired biomedical and biotechnological applications.
We intend to provide students with a comprehensive overview of current Molecular Bioinformatics topics.
In practical labs, students are encouraged to develop small protocols on the research topics covered.
We intend to provide students with a comprehensive overview of current Molecular Bioinformatics topics.
In practical labs, students are encouraged to develop small protocols on the research topics covered.
The UC aims to develop in the students skills in the creation of new business ventures in the area of life sciences, integrating both a theoretical and a strong practical component. The presentation and discussion of concepts and methodologies, will aim to validate the application of the market potential of a concrete business project in the area of biosciences.
At the end of the course, students should:
1 Understanding the challenges of the creation, validation and start-up of new business process projects;
- To identify the role of Chemistry in the context of Nanosciences and Nanotechnology.
- To gain knowledge in methods of production of nanomaterials and characterization techniques for nanomaterials analysis.
- To select the most appropriate experimental techniques for the characterization of each nanomaterial.
- To identify the technological applications of each type of nanomaterial.
- To identify potential risks, regulations, and ethical issues associated with the impact of the production and commercialization of nanotechnology-based products on society.
- To read and interpret critically scientific papers in the areas of Nanosciences and Nanotechnology.