Challenges and innovations in chiral drugs in an environmental and bioanalysis perspective

• Type: Another Publication in an International Scientific Journal
• Date: 2021

Authors

Barreiro, JC (Author) Other; Tiritan M.E. (Author) FFUP; Cass, QB (Author) Other

Journal

Title: TrAC - Trends in Analytical Chemistry

Vol. 142

ISSN: 0165-9936

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 8 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-00V-8WM

DOI: 10.1016/j.trac.2021.116326

Abstract (EN): The boundary of the chiral environmental, forensic and bioanalysis has been critically presented in this review. Important advances regarding chiral screening technology and their impact on method devel-opment and applications have been pointed out. The complexity of merging high efficiency enantiose-lectivity separation with the selected sample matrix and the intended goal of the analysis is not a trivial task and in many cases the application of the method is the main novelty. Regardless of the complexity of new applications on chiral separation analysis, the trend is towards reaching higher levels of detectability and lower sample volumes. An assorted variety of methods applications in environmental and bio-analysis, including demand in forensic analysis is herein concisely discussed.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9