Immunology

Code:

LCN2209

Acronym:

IMUNO

Keywords
Classification	Keyword
OFICIAL	Health Sciences

Instance: 2024/2025 - 2S

Active?	Yes
Web Page:	https://moodle2425.up.pt/course/view.php?id=315
Course/CS Responsible:	Nutrition Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
CNUP	107	Official plan	2	-	3	28	81

Teaching language

Suitable for English-speaking students

Objectives

Acquire the knowledge of basic mechanisms of the immune response, including the biological response to the exogenous or endogenous agents, in human pathology and it dependence on Human Nutrition.

Learning outcomes and competences

To integrate the knowledge of the basic mechanisms of the immune response in the pathogenesis of human diseases. To understand the basic principles of clinical and laboratorial diagnosis and or the treatment of immune diseases.

At the end of this Curricular Unit students are expected to acquire the following competences: A - To demonstrate knowledge of immune dysfunction in a clinical perspective and of immunological therapies; B – To apply basic immunology concepts in the interpretation of human pathology; C – To describe common immunopathological conditions; D – To be able to communicate scientific and technical information; E – To demonstrate skills on continuous personal development.

Working method

Presencial

Program

Basic Immunology

1. The Immune system - components and functional organization;
2. Antigens - immunogenicity and antigen processing;
3. B lymphocytes - development and antibody synthesis;
4. Antibodies – structure and function;
5. T lymphocytes - ontogenesis, antigen recognition immunoregulatory role;
6. Major histocompatibility complex - structure and participation on the afferent, central and immune responses;
7. Immunological  tolerance - mechanisms  of central  and  peripheral immune tolerance;
8. Regulation of the immune response - by the antigen, intrinsic, neuroendocrine and genetic;

Clinical Immunology

1. Primary immunodeficiencies - general characteristics and evaluation.
2. Secondary immunodeficiency - Acquired Immunodeficiency Syndrome
3. Hypersensitive diseases (type I to IV) and immunopathology: Allergic asthma
4. Anaphylaxis
5. Urticaria and Food Allergy
6. Auto-immune diseases - General characteristics, immunopathology, laboratory evaluation;  

Immunonutrition

1. Diet and gut microbiota
2. Immunology of diabetes
3. Obesity and asthma
4. Inflammatory bowel disease
5. Inflammation and cardiovascular risk
6. Inflammation and sleep apnea
7. Nutritional modulation of exercise induced immunepression

 

Mandatory literature

Arosa Fernando A. 340; Fundamentos de imunologia. ISBN: 978-972-757-856-6

Complementary Bibliography

Judy Owen , Jenni Punt , Sharon Stranford ; Kuby Immunology, WH Freeman, 2013. ISBN: ISBN-13: 978-1-4292-1919-8

Teaching methods and learning activities

The themes will be approached by 2 lectures per week – 1 hour duration each.

keywords

Health sciences > Medical sciences > Medicine > Immunology

Evaluation Type

Distributed evaluation without final exam

Assessment Components

Designation	Weight (%)
Exame	80,00
Trabalho prático ou de projeto	20,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Estudo autónomo	55,00
Frequência das aulas	20,00
Trabalho escrito	5,00
Total:	80,00

Eligibility for exams

Attendance Rules as Academic Regulations of Nutrition and Food Sciences, University of Porto

Calculation formula of final grade

The classification results from the i) final exam (80%) and ii) presentation of a monograph (20%).

i) The final exam will consist of a theoretical written test with multiple-choice questions (ETfinal). Will be considered approved by the theoretical examination students who obtain a minimum score of 10 points. 

ii) The monograph consists of the submission and presentation of a topic indicated by the docent 

Observations

Opening hours: Thursdays from 9am to 4pm at the FMUP Immunology Service or at a time to be agreed