General and Nutritional Pathology

Code:

CN31006

Acronym:

PGNUT

Keywords
Classification	Keyword
OFICIAL	Health Sciences

Instance: 2013/2014 - 1S

Active?	Yes
Course/CS Responsible:	Nutrition Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
CNUP	81	Plano oficial	3	-	4	42	108

Teaching language

Portuguese

Objectives

Students are intended to learn the anatomo-pathological language (words/concepts) and acquire observation/description skills, as well as the ability to think in biopathological terms when interpreting and solving problems.

Learning outcomes and competences

See Objectives.

Working method

Presencial

Program

Introduction to General and Nutritional Pathology. Concept of reversible and irreversible injury. Causes of injury. Cell adaptation. Atrophy, hypertrophy, hyperplasia, metaplasia and intracellular accumulations. Proliferation and differentiation. Control of the cell cycle. Intestinal tract as a paradigm. Necrosis and apoptosis. Control of apoptosis. Regeneration and healing. Atheroma, atherosclerosis and arteriosclerosis. Vasculitis. Infarcts. Introduction to inflammation. Acute inflammation. Chronic inflammations. Granulomatous inflammations. Crohn D. and ulcerative colitis as paradigms Introduction to immunopathology. AIDS as paradigm. Malabsorption and malnutrition. Celiac disease as paradigm Introduction to obesity pathology. Pancreatitis. Diabetes mellitus. Chronic hepatic illness. Hepatic cirrhosis. Introduction to neoplasia. Oncogenes, oncosuppressor genes and genes which are susceptible to cancer. Neoplasic initiation, promotion and progression. Angiogenesis. Invasion and metastases. Environmental carcinogenesis. Primary and secondary prevention. Dietary/nutritional elements and cancer. Carcinogenesis of respiratory passages and of the oesophagus. Carcinogenesis of the stomach. Carcinogenesis of the colon and the rectum Viral carcinogenesis - Carcinoma of the cervix. Pathology of food imbalance. Hypometabolic, hypermetabolic and mixed conditions. Introduction to food toxicological pathobiology Pathology of aging

Mandatory literature

Robin Cooke; Brian Stewart; Colour atlas of anatomical pathology - 3ª edição, Churchill Livingstone, 2003. ISBN: 0443073600
Kumar Vinay 340; Robbins basic pathology. ISBN: 0-7216-9274-5
Cooke Robin A.; Colour atlas of anatomical pathology. ISBN: 0-443-05062-7
Kumar Vinay 340; Robbins basic pathology. ISBN: 978-1-4377-1781-5

Teaching methods and learning activities

Classes with initial explanation of 50 to 55 minutes, followed by a discussion of 5 to 10 minutes (1 hour a week). Sessions (2 hours, once a week) based on prior observation of selected documents which are made available (these documents include images of anatomo-pathological material on computer media: pieces of autopsy and surgical pathology, as well as images of histology, histochemistry, immunohistochemistry and ultrastructure) followed by discussion with the teacher.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	60,00
Participação presencial	0,00
Trabalho laboratorial	40,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Frequência das aulas	140,00
Total:	140,00

Eligibility for exams

According to the CU instructions.

Calculation formula of final grade

Final classification:
a) Exam (computer-based) with 60 multiple choice questions about program contents (12.0/20 points)-60 minutes. Each correct answer=0.2 points; wrong answer=minus 0.1 point. Non-answered questions=0 points.
b) Students with 24 or more attendancies to all classes (1 hour + 2 hour classes) who submit via Moodle until Friday (12:00 p.m.) of the first week of classes that they read and understood the CU instructions get a 0.5 point bonus. Students with more than 25% absences to all classes are not allowed to take the final exam (i.e. these students failed the Curricular Unit).  
c) Continuous evaluation (see Métodos de Ensino): 4.0/20 points.
d) Powerpoint presentations (see Provas e Trabalhos Especiais): 4.0/20 points.

Final classification formula: a)+b)+c)+d).

Important notes:

1-There are minimal points to pass the evaluations: a) ≥ 5.5/12.0 and c) + d):  ≥ 3.5/8.0.

2-Students with more than 15.0/20 points can ask for oral exam; if they do not perform this exam the final classification will be 15.0/20 points. There is no oral exam for students with less than 10.0/20 points after the final classification formula. Students with less than 15.0/20 points can perform one more exam (see Avaliação Especial, TE, DA...).

Observations

Compulsory Language of Teaching: Portuguese