General and Nutritional Pathology

Code:

CN31006

Acronym:

PGNUT

Keywords
Classification	Keyword
OFICIAL	Health Sciences

Instance: 2009/2010 - 1S

Active?	Yes
Course/CS Responsible:	Nutrition Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
CNUP	70	Plano oficial	3	-	4	42	108

Teaching language

Portuguese

Objectives

Students are intended to learn the anatomo-pathological language (words/concepts) and acquire observation/description skills, as well as the ability to think in biopathological terms when interpreting and solving problems.

Program

Introduction to General and Nutritional Pathology. Concept of reversible and irreversible injury. Causes of injury. Cell adaptation. Atrophy, hypertrophy, hyperplasia, metaplasia and intracellular accumulations. Proliferation and differentiation. Control of the cell cycle. Intestinal tract as a paradigm. Necrosis and apoptosis. Control of apoptosis. Regeneration and healing. Atheroma, atherosclerosis and arteriosclerosis. Vasculitis. Infarcts. Introduction to inflammation. Acute inflammation. Chronic inflammations. Granulomatous inflammations. Crohn D. and ulcerative colitis as paradigms
Introduction to immunopathology. AIDS as paradigm.
Malabsorption and malnutrition. Celiac disease as paradigm
Introduction to obesity pathology. Pancreatitis. Diabetes mellitus. Chronic hepatic illness. Hepatic cirrhosis.
Introduction to neoplasia. Oncogenes, oncosuppressor genes and genes which are susceptible to cancer. Neoplasic initiation, promotion and progression. Angiogenesis. Invasion and metastases. Environmental carcinogenesis. Primary and secondary prevention. Dietary/nutritional elements and cancer. Carcinogenesis of respiratory passages and of the oesophagus. Carcinogenesis of the stomach. Carcinogenesis of the colon and the rectum
Viral carcinogenesis - Carcinoma of the cervix.
Pathology of food imbalance. Hypometabolic, hypermetabolic and mixed conditions.
Introduction to food toxicological pathobiology
Pathology of aging

Mandatory literature

Cooke Robin A.; Colour atlas of anatomical pathology. ISBN: 0-443-05062-7
Kumar Vinay 340; Robbins basic pathology. ISBN: 0-7216-9274-5

Teaching methods and learning activities

Theoretical classes with initial explanation of 50 to 55 minutes, followed by a discussion of 5 to 10 minutes (twice a week). Theoretical-practical sessions (once a week) based on prior observation (45 minutes) of selected documents which are made available (these documents include images of anatomo-pathological material on computer media: pieces of autopsy and surgical pathology, as well as images of histology, histochemistry, immunohistochemistry and ultrastructure) followed by discussion (45 minutes) with the teacher.

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Description	Type	Time (hours)	Weight (%)	End date
Attendance (estimated)	Participação presencial	42,00
	Total:	-	0,00

Observations

Compulsory
Language of Teaching : Portuguese