Organic Chemistry

Code:

CN11004

Acronym:

QORG

Keywords
Classification	Keyword
OFICIAL	Health Sciences
OFICIAL	Physical Sciences

Instance: 2018/2019 - 1S

Active?	Yes
Course/CS Responsible:	Nutrition Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
CNUP	104	Plano oficial	1	-	5,5	56	148,5

Teaching language

Suitable for English-speaking students

Objectives

The contributions that each one of you will receive for their scientific, professional and human formation are not in any way confined to school walls.

The main agent of that training is always each one of you asking questions and finding answers that will form part of the personal knowledge collected from multiple sources. The variety of these sources is increasingly wide in a world that, with the recent advances in information technology, increasingly resembles a large village. In old times the school could play the role of privileged and unquestioned source of knowledge, at present this role no longer makes sense.

The role of schools and teachers, in our view, is to encourage and assist the students in pursuit of their own training and to facilitate this process by proposing topics for study which act as stages of its formation. The choice of these themes, and the depth with which they are developed, is not an abstract exercise, impartial and inflexible, but rather the result of a series of questionable choices and continually reshaped by new challenges that science is proposing and also by personal experience of teachers, either as teachers or as researchers.

Being part of a series of topics proposed for the reflection of the students during their degree in Nutritional Sciences, this curricular unit of organic chemistry is very close to the curricular units of Biochemistry I (also taught in the first year of the course) and Biochemistry II and Biochemistry III (bought taught in the second year).

The same teaching staff is responsible for the four curricular units, with organic chemistry being understood by this team as a sub-step (in fact the first!) in the process of language acquisition needed for Biochemistry and in the knowledge of their methods of study and its fundamental laws.

In this sub-step we put particular emphasis on (1) the study of the chemical structures of the living organisms and (2) the study of general aspects of chemistry and organic chemistry, with particular interest for understanding the chemical transformation occurring in living organisms.

Learning outcomes and competences

At the end of this Curricular Unit, students should have acquired theoretical and/or practical skills to enable them:

• To identify the diversity of the composition of living organisms,

• To identify, understand and describe (theoretically and/or in the laboratory) the different structure and reaction characteristics of the molecules present in living organisms and/or food,

• To understand the general mechanisms of enzymatic catalysis and regulation.

Working method

Presencial

Pre-requirements (prior knowledge) and co-requirements (common knowledge)

Not applicable.

Program

Diversity of the composition of living organisms: organic and inorganic components.

Structures and reactional characteristics of molecules of living organisms and/or foods: functional groups and characteristic reactions of their identification; structure of carbohydrates, lipids and proteins; isomerism; glycosylation and glycation of proteins and lipids; water; acid-base equilibrium; oxidation-reduction reaction; kinetics and chemical reactions; osmotic balance; mineral water content; dietary antioxidants and food chemical changes.

General mechanisms of catalysis and enzyme regulation: enzymes and enzymatic reactions. Immobilization of enzymes. Alkaline phosphatase.

Mandatory literature

Nelson David L.; Lehninger Principles of Biochemistry. ISBN: 978-0-7167-7108-1
Patrick Graham L.; Beginning organic chemistry. ISBN: 0-19-855936-4
Jones Jr. Maitland; Organic chemistry. ISBN: 978-0-393-93713-8

Complementary Bibliography

Thomas M. Devlin; Textbook of Biochemistry with Clinical Correlations, 2010
Brody Tom; Nutritional biochemistry. ISBN: 0-12-134836-9
Rodwell VW, Bender DA, Botham KM, Kennelly PJ, Weil PA; Harper's Illustrated Biochemistry

Teaching methods and learning activities

Teaching methodologies:

Weekly/per student: 2 lectures of 1 h each (for 13 weeks) and 1 practical session of 2 h (for 12 weeks).

First evalution period:

Evaluation will be performed continously during the semester without final exam and will be composed of:

a) 3 written interim assessment tests (IAs): 18 out of 20 points, and

b) laboratorial performance: 2 out of 20 points.

IAs (with maximum duration of 1 h) will be performed at the "Anfieatro Norte" and "Anfiteatro Nascente" of FMUP, at 9h30 am of the following days:

. 26/10/2018

. 16/11/2018

 . Information will be provided later.

Second evalution period:

a) written test (maximum duration 2 h): 18 out of 20 points, and

b) laboratorial performance: 2 out of 20 points.

Evaluation Type

Distributed evaluation without final exam

Assessment Components

Designation	Weight (%)
Participação presencial	10,00
Teste	90,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Estudo autónomo	102,00
Frequência das aulas	26,00
Trabalho laboratorial	26,00
Total:	154,00

Eligibility for exams

Minimum classification in each of the 3 interim assessments: 8 points (out of 20 points).
Attendance at least of 75% of laboratorial classes.

Calculation formula of final grade

First evalution period

FC = (0.35 x IA1 + 0.20 x IA2 + 0.35 x IA3) + 0.1 x LP

FC - final classification (ou of 20 points)
IA1 - classification obtained in the first interim assessment (out of 20 points)
IA2 - classification obtained in the second interim assessment (out of 20 points)
IA3 - classification obtained in the third interim assessment (out of 20 points)
LP - classification of the performance obtained at the laboratorial sessions (out of 20 points)

Minimum classification in each of the 3 interim assessments: 8 points (out of 20 points).


Second evalution period

FC= 0.9 x FE + 0.1 x LP

FC - final classification (out of 20 points)
FE- classification of the final exam (out of 20 points)
LP - classification of the performance obtained at the laboratorial sessions (out of 20 points)