Immunology

Code:

CN22004

Acronym:

IMUNO

Keywords
Classification	Keyword
OFICIAL	Health Sciences

Instance: 2015/2016 - 2S

Active?	Yes
Web Page:	https://moodle.up.pt/course/view.php?id=66
Course/CS Responsible:	Nutrition Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
CNUP	95	Plano oficial	2	-	3	28	81

Teaching language

Suitable for English-speaking students

Objectives

Acquire the knowledge of basic mechanisms of the immune response, including the biological response to the exogenous or endogenous agents, in human pathology and it dependence on Human Nutrition.

Learning outcomes and competences

To integrate the knowledge of the basic mechanisms of the immune response in the pathogenesis of human diseases. To understand the basic principles of clinical and laboratorial diagnosis and or the treatment of immune diseases.

At the end of this Curricular Unit students are expected to acquire the following competences: A - To demonstrate knowledge of immune dysfunction in a clinical perspective and of immunological therapies; B – To apply basic immunology concepts in the interpretation of human pathology; C – To describe common immunopathological conditions; D – To be able to communicate scientific and technical information; E – To demonstrate skills on continuous personal development.

Working method

Presencial

Program

Basic Immunology

1. The Immune system - components and functional organization;
2. Antigens - immunogenicity and antigen processing;
3. B lymphocytes - development and antibody synthesis;
4. Antibodies – structure and function;
5. T lymphocytes - ontogenesis, antigen recognition immunoregulatory role;
6. Major histocompatibility complex - structure and participation on the afferent, central and immune responses;
7. Immunological  tolerance - mechanisms  of central  and  peripheral immune tolerance;
8. Regulation of the immune response - by the antigen, intrinsic, neuroendocrine and genetic;

Clinical Immunology

1. Primary immunodeficiencies - general characteristics and evaluation.
2. Secondary immunodeficiency - Acquired Immunodeficiency Syndrome
3. Hypersensitive diseases (type I to IV) and immunopathology: Allergic asthma
4. Anaphylaxis
5. Urticaria and Food Allergy
6. Auto-immune diseases - General characteristics, immunopathology, laboratory evaluation;  

Immunonutrition

1. Diet and gut microbiota
2. Immunology of diabetes
3. Obesity and asthma
4. Inflammatory bowel disease
5. Inflammation and cardiovascular risk
6. Inflammation and sleep apnea
7. Nutritional modulation of exercise induced immunepression

 

Mandatory literature

Arosa Fernando A. 340; Fundamentos de imunologia. ISBN: 978-972-757-856-6

Complementary Bibliography

Judy Owen , Jenni Punt , Sharon Stranford ; Kuby Immunology, WH Freeman, 2013. ISBN: ISBN-13: 978-1-4292-1919-8

Teaching methods and learning activities

The themes will be approached by 2 lectures per week – 1 hour and 30 minutes duration each.

keywords

Health sciences > Medical sciences > Medicine > Immunology

Evaluation Type

Distributed evaluation with final exam

Assessment Components

Designation	Weight (%)
Exame	85,00
Trabalho escrito	15,00
Total:	100,00

Amount of time allocated to each course unit

Designation	Time (hours)
Elaboração de relatório/dissertação/tese	11,00
Estudo autónomo	52,00
Frequência das aulas	21,00
Total:	84,00

Eligibility for exams

Attendance Rules as Academic Regulations of Nutrition and Food Sciences, University of Porto

Calculation formula of final grade

In the discipline, students may choose a i) distributed assessing or ii) final exam.

i) The distributed evaluation will comprise two theoretical examinations (ET 1 and 2) of multiple choice questions, all in the range of 0 to 20 values. The exams will be scheduled on days and times in this plan.The combined result of the two examination will represent 85% of the final classification (CF). The remaining 15%, result from the evaluation of a written short report (MNG), up to 1000 words and 10 references in a previous given theme. Students who obtain the rating in the distributed evaluation equal to or higher than 10 are excused from the theory test, being this classification replaced by the distributed evaluation. Therefore, for students choosing the distributed evaluation, final score will be as follows:CF = 0.85*((ET1+ET2)/2)+0.15*MNG

ii) The final exam will consist of a theoretical written test consisting of multiple-choice questions (ETfinal). Will be considered approved in the theoretical examination students who obtain a minimum score of 10 points. Students who wish to improve their grade of distributed evaluation described above, will have to undergo this theoretical exam. In this case, students will dismiss their distributed classification. The final classification (CF) will be calculated using the formulas: CF = 1*ETfinal

 

Observations

Period of attendance and educational assistance: tuesdays (9 to 12 am) and fridays (10 to 12am) in the Department of Immunology of the Faculty of Medicine