Immunology

Code:

CN22004

Acronym:

IMUNO

Keywords
Classification	Keyword
OFICIAL	Health Sciences

Instance: 2011/2012 - 2S

Active?	Yes
Course/CS Responsible:	Nutrition Sciences

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
CNUP	128	Plano oficial	2	-	3	28	81

Teaching language

Portuguese

Objectives

Acquire the knowledge of basic mechanisms of the immune response, including the biological response to the exogenous or endogenous agents, in human pathology and it dependence on Human Nutrition.

Program

1.Immunity - concept and biopathological relevance;
2.The Immune system - components and functional organization;
3.B lymphocytes - development and antibody synthesis;
4.T lymphocytes - ontogenesis, antigen recognition immunoregulatory role;
5.Antigens - immunogenicity and antigen processing;
6.Major histocompatibility complex - structure and participation in the afferent, central and immune response;
7.Immunological tolerance - mechanisms of central and peripheral immune tolerance;
8.Effector mechanisms and the amplification of the immune response - inflammatory cytokines, chemokines. Inflammation and cellular recruitment;
9.Cytokines – regulatory role in B and T lymphocyte response;
10.Regulation of the immune response
11.Immunity and infection – the immune response to infection, escape mechanisms of microorganisms;
12.Primary immunodeficiencies - general characteristics and infection;
13.Secondary immunodeficiencies - Acquired Immunodeficiency Syndrome;
14.Hypersensitivity - general characteristics;
15.Hypersensitive diseases (type I to IV);
16.Auto-immune diseases - general characteristics, immunopathology;
17.Organ-specific and systemic auto-immune diseases;
18.Tumor immunology - immune response to tumors antigens and immune escape;

Main Bibliography

Immunology - Roitt, Brostoff, Male eds. 6th Edition. Mosby International.ISBN 0 7234 3189.2; 2001;
Immunology, Goldsby RA, Kindt TJ, Osborne BA, Kuby J. eds. 5th ed, 2003 WH Freeman and Co, ISBN 0 7167 4947 5;

Complementary Bibliography

Immunobiology. Janeway, Travers, Walport, Shlomchik eds. 6th Edition, 2004, Garland Churchill Livingstone. ISBN 0 8153 4101 6;

Teaching methods and learning activities

The themes will be approached by 2 lectures per week – 1 hour and 30 minutes duration each.

Evaluation Type

Evaluation with final exam

Eligibility for exams

Students with 9.5 values in final exam are readily passed.

Calculation formula of final grade

Students with 9.5 values in final exam are readily passed.