Extending the reservoir of bla (IMP-5): the emerging pathogen Acinetobacter bereziniae

• Tipo: Artigo em Revista Científica Internacional
• Data: 2015

Autores

Grosso, F (Autor) Outra; Silva, L (Autor) Outra; Sousa, C (Autor) Outra; Ramos, H (Autor) Outra; Quinteira, S (Autor) FCUP; Luisa Peixe (Autor) FFUP

Revista

Título: Future Microbiology

Vol. 10

Páginas: 1609-1613

ISSN: 1746-0913

Editora: Future Medicine Ltd.

Indexação

ISI Web of Knowledge - 11 Citações

Scopus - 11 Citações

Outras Informações

ID Authenticus: P-00G-TV8

DOI: 10.2217/fmb.15.88

Abstract (EN): Aim:Acinetobacter bereziniae clinical relevance is starting to be recognized; however, very few descriptions of its carbapenem resistance currently exist. Here we characterize two carbapenem-resistant A. bereziniae isolates. Materials & methods: Isolates were obtained from environmental and clinical samples. Carbapenemases were searched by phenotypic, biochemical and PCR assays. Clonality was studied by ApaI-PFGE and genetic location for carbapenemase genes were assessed by I-CeuI and S1 hybridizations. Results: Isolates were not clonally related but both produced the exclusively Portuguese' IMP-5, with the clinical isolate also producing an OXA-58. The carbapenemase genes were plasmid located. Conclusion: Our results emphasize the role of non-baumannii Acinetobacter species as important reservoirs of clinically relevant resistance genes that could also contribute to their emergence as nosocomial pathogens.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5