Production of phenolics by in vitro cultures of Hypericum perforatum: A case study

• Type: Article in International Conference Proceedings Book
• Date: 2002

Authors

Dias, ACP (Author) Other; Ferreira, MF (Author) Other

Conference proceedings International

Title: NATURAL PRODUCTS IN THE NEW MILLENNIUM: PROSPECTS AND INDUSTRIAL APPLICATION

Pages: 367-374

Meeting of the Phytochemical-Society-of-Europe

LISBON, PORTUGAL, APR 02-05, 2000

Indexing

ISI Web of Knowledge - 1 Citation

Scientific classification

FOS: Natural sciences > Biological sciences

Other information

Authenticus ID: P-000-RN4

Abstract (EN): Calli and shoot cultures of H. perforatum were established. The phenolic compounds accumulated in these types of cultures, over a period of four years, were compared by HPLC-DAD with those produced by in vivo plants. Calli and suspended cells did not accumulate detectable amounts of hypericins or phloroglucinols, independently of the several hormonal variants tested. The major phenolics accumulated by these type of biomass were xanthones and some luteolin type flavones. Besides these types of compounds, shoot cultures also accumulated hypericins, hyperforins, flavonols and caffeioylquinic acids. In shoot cultures the production of hypericins decreased continuously during the 4-year culture period whereas hyperforins accumulation remained similar.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8