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Gastric emptying and antireflux surgery

Title
Gastric emptying and antireflux surgery
Type
Article in International Scientific Journal
Year
2011
Authors
Jose Estevao Costa
(Author)
FMUP
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Ana Catarina Fragoso
(Author)
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Maria Jose Prata
(Author)
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Miguel Campos
(Author)
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Eunice Trindade
(Author)
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Jorge Amil Dias
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Ana Maria Brazao
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Journal
Vol. 27
Pages: 367-371
ISSN: 0179-0358
Publisher: Springer Nature
Indexing
Publicação em ISI Proceedings ISI Proceedings
Publicação em ISI Web of Science ISI Web of Science
Pubmed / Medline
Scientific classification
FOS: Medical and Health sciences > Clinical medicine
Other information
Authenticus ID: P-002-SYM
Abstract (EN): Absence of consistent data on the outcome of gastric emptying after fundoplication raises concerns about preoperative workup and surgical management. This study assessed how gastric emptying evolves after isolated fundoplication in order to determine whether a preoperative investigation and/or a concurrent gastric drainage procedure are justified. Eleven children with GERD underwent both pre- and post-operative gastric emptying scintigraphy. No gastric drainage procedures were added to fundoplication. Scintigraphy was performed according to a standardized protocol (labeled meal, 300 ml + 500 mu Ci (99m)Tc/m(2) bsa). Half-emptying time (t (1/2)), emptying rate and fractions of retention are expressed as the median followed by the [range]; statistical significance level was set at 5%. Postoperative t (1/2) (min) showed a much smaller dispersion and was significantly lower than preoperative one (76 [56;101] vs. 107 [57;186], p = 0.04) with a variation of -48 [-105;19]; there was no individual correlation between pre- and post-operative measurements (r = 0.25). The proportion of patients with delayed gastric emptying (t (1/2) > 100) was significantly lower in the postoperative scintigraphy (9 vs. 55%, p = 0.03). The postoperative emptying rate (%/h) was significantly faster (35.1 [18.9;41.7] vs. 28.5 [16.3;38.7], p = 0.05). The retentions (%) at 30 and 60 min were similar; at 90 and 120 min were significantly lower after surgery (45 [35;54] and 32 [24;46] vs. 53 [33;78] and 41 [25;66], p = 0.03 and 0.05). Gastric emptying accelerates significantly after fundoplication with a shift to normal values in the vast majority of patients. Scintigraphy does not predict the postoperative outcome. Therefore, concomitant drainage procedures seem unnecessary and preoperative gastric emptying study not useful.
Language: English
Type (Professor's evaluation): Scientific
Contact: estevao.costa@hsjoao.min-saude.pt
No. of pages: 5
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