Gastric inflammatory myofibroblastic proliferation in children

• Type: Article in International Scientific Journal
• Date: 1998

Authors

Estevão-Costa J (Author) FMUP; Correia-Pinto J (Author) Other; Rodrigues FC (Author) Other; Carvalho JL (Author) Other; Campos M (Author) FMUP; Dias JA (Author) Other; Carneiro F (Author) FMUP; Santos NT (Author) Other

Journal

Title: Pediatric Surgery International

Vol. 13

Pages: 95-99

ISSN: 0179-0358

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 32 Citations

ISI Web of Science

Scopus - 29 Citations

Pubmed / Medline

Scientific classification

FOS: Medical and Health sciences > Other medical sciences

Other information

Authenticus ID: P-001-8ES

DOI: 10.1007/s003830050257

Abstract (EN): Gastric inflammatory myofibroblastic proliferation (IMP) is an extremely rare entity in children, which to our knowledge has only been mentioned in case reports. We describe the ninth pediatric case and review the literature concerning the etiology, clinical and laboratory features, pathology, treatment, and outcome. There has been a predominance in preschool females. Abdominal pain, upper gastrointestinal hemorrhage, and an abdominal mass, either isolated or associated, have been the main clinical features. Iron-deficiency anemia has been a constant finding. Lesions are elevated and involve the full thickness of the gastric wall, usually with ulceration of the luminal surface; extragastric extension suggesting malignancy is frequent. Diagnosis is made by histology after surgical excision. There was no mortality directly related to gastric IMP, and only one case recurred after surgical excision. The pathogenesis is controversial, but the finding of Helicobacter pylori in our case may indicate an inflammatory origin, Awareness: of this benign lesion and its mimicry of malignancy is important so that inappropriately aggressive therapy can be avoided.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5