In vitro cytocompatibility of osteoblastic cells cultured on chitosan-organosiloxane hybrid membrane

• Type: Another Publication in an International Scientific Journal
• Date: 2004

Authors

Y. Shirosaki (Author) Other; K. Tsuru (Author) Other; S. Hayakawa (Author) Other; A. Osaka (Author) Other; Maria Ascensão Lopes (Author) FEUP; José Domingos Santos (Author) FEUP; Maria Helena Fernandes (Author) FMDUP

Indexing

ISI Web of Knowledge - 4 Citations

ISI Web of Science

Scopus - 3 Citations

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

Other information

Authenticus ID: P-000-CBQ

DOI: 10.4028/www.scientific.net/KEM.254-256.857

Abstract (EN): Chitosan-silicate hybrids were synthesized using gamma-glycidoxypropyltrimethoxysilane (GPSM) as the agent to cross-link the chitosan chains. Fourier-transform infrared (FT-IR) spectroscopy was used to analyze the structures of the hybrids. The swelling ability and the cytocompatibility of the hybrids were investigated as a function of the GPSM concentration. The swelling of the hybrids was suppressed by addition of GPSM. MG63 human osteoblastic cells were cultured on the hybrids. The adhesion and proliferation of the MG63 cells cultured on the chitosan-GPSM hybrid surface were improved comparing to that on chitosan membrane, regardless the GPSM concentration.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4