Joint ESPGHAN/NASPGHAN Guidelines on Childhood Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis

• Type: Article in International Scientific Journal
• Date: 2024

Authors

Papadopoulou, A (Author) Other; Amil-Dias, J (Author) Other; Auth, MKH (Author) Other; Chehade, M (Author) Other; Collins, MH (Author) Other; Gupta, SK (Author) Other; Gutierrez-Junquera, C (Author) Other; Orel, R (Author) Other; Vieira, MC (Author) Other; Zevit, N (Author) Other; Atkins, D (Author) Other; Bredenoord, AJ (Author) Other; Carneiro F (Author) FMUP; Dellon, ES (Author) Other; Gonsalves, N (Author) Other; Menard-Katcher, C (Author) Other; Koletzko, S (Author) Other; Liacouras, C (Author) Other; Marderfeld, L (Author) Other; Oliva, S (Author) Other; Ohtsuka, Y (Author) Other; Rothenberg, ME (Author) Other; Strauman, A (Author) Other; Thapar, N (Author) Other; Yang, GY (Author) Other; Furuta, GT (Author) Other

Journal

Title: Journal of Pediatric Gastroenterology and Nutrition

Vol. 78

Pages: 122-152

ISSN: 0277-2116

Publisher: Wolters Kluwer Health

Indexing

ISI Web of Knowledge - 2 Citations

Other information

Authenticus ID: P-010-0JQ

DOI: 10.1097/mpg.0000000000003877

Abstract (EN): IntroductionEosinophilic gastrointestinal disorders beyond eosinophilic esophagitis (non-EoE EGIDs) are rare chronic inflammatory disorders of the gastrointestinal (GI) tract. Diagnosis is based on clinical symptoms and histologic findings of eosinophilic inflammation after exclusion of a secondary cause or systemic disease. Currently, no guidelines exist for the evaluation of non-EoE EGIDs. Therefore, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) formed a task force group to provide consensus guidelines for childhood non-EoE EGIDs.MethodsThe working group was composed of pediatric gastroenterologists, adult gastroenterologists, allergists/immunologists, and pathologists. An extensive electronic literature search of the MEDLINE, EMBASE, and Cochrane databases was conducted up to February 2022. General methodology was used in the formulation of recommendations according to the Appraisal of Guidelines for Research and Evaluation (AGREE) II and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to meet current standards of evidence assessment.ResultsThe guidelines provide information on the current concept of non-EoE EGIDs, disease pathogenesis, epidemiology, clinical manifestations, diagnostic and disease surveillance procedures, and current treatment options. Thirty-four statements based on available evidence and 41 recommendations based on expert opinion and best clinical practices were developed.ConclusionNon-EoE EGIDs literature is limited in scope and depth, making clear recommendations difficult. These consensus-based clinical practice guidelines are intended to assist clinicians caring for children affected by non-EoE EGIDs and to facilitate high-quality randomized controlled trials of various treatment modalities using standardized, uniform disease definitions. image

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 31