Silica-Based Nanomaterials for Diabetes Mellitus Treatment

• Type: Another Publication in an International Scientific Journal
• Date: 2023

Authors

Marinheiro, D (Author) Other; Martel, F (Author) FMUP; Ferreira, BJML (Author) Other; Daniel-da-Silva, AL (Author) Other

Journal

Title: Bioengineering

Vol. 10 No. 3

Final page: 40

Publisher: MDPI

Indexing

ISI Web of Knowledge - 0 Citations

Scopus

Other information

Authenticus ID: P-00X-VCF

DOI: 10.3390/bioengineering10010040

Abstract (EN): Diabetes mellitus, a chronic metabolic disease with an alarming global prevalence, is associated with several serious health threats, including cardiovascular diseases. Current diabetes treatments have several limitations and disadvantages, creating the need for new effective formulations to combat this disease and its associated complications. This motivated the development of therapeutic strategies to overcome some of these limitations, such as low therapeutic drug bioavailability or poor compliance of patients with current therapeutic methodologies. Taking advantage of silica nanoparticle characteristics such as tuneable particle and pore size, surface chemistry and biocompatibility, silica-based nanocarriers have been developed with the potential to treat diabetes and regulate blood glucose concentration. This review discusses the main topics in the field, such as oral administration of insulin, glucose-responsive devices and innovative administration routes.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 23