Intensification strategies for cytostatics degradation by ozone-based processes in aqueous phase

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Costa, AL (Author) Other; Gouveia, TIA (Author) FEUP; Manuel Fernando R Pereira (Author) FEUP; Silva, Adrian (Author) FEUP; Luis Madeira (Author) FEUP; Arminda Alves (Author) FEUP; Mónica Santos (Author) FEUP

Journal

Title: Journal of Hazardous Materials

Vol. 440

ISSN: 0304-3894

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Associated Projects

Healthy Waters - Healthy Waters - Identification, Elimination, Social Awareness and Education of Water Chemical and Biological Micropollutants with Health and Environmental Implications

Other information

Authenticus ID: P-00X-2TJ

DOI: 10.1016/j.jhazmat.2022.129743

Abstract (EN): Over the past decade there has been an increasing concern on the presence of cytostatics (also known as anti-cancer drugs) in natural waterbodies. The conventional wastewater treatments seem not to be effective enough to remove them, and therefore new processes must be considered. This work investigates the performance of ozonation (O3), catalytic ozonation (O3/Fe2+) and peroxone (O3/H2O2) processes, under dark or UV radiation conditions, for the degradation of cytostatics of worldwide concern. The degradation of bicalutamide (a repre-sentative of recalcitrant cytostatics) was firstly assessed in batch and then in a tubular column reactor (continuous flow mode runs) using a wastewater treatment plant (WWTP) secondary effluent. Bicalutamide removal ranged between 66 % (O3) and 98 % (O3/H2O2/UV) in continuous flow mode runs, the peroxone process being the most effective. The performance of these processes was then assessed against a mixture of twelve cytostatics of worldwide concern spiked in the WWTP effluent (25-350 ng/L). After treatment, seven cytostatics were completely removed, whereas the five most recalcitrant ones were eliminated to an extent of 8-92 % in O3/ H2O2, and 44-95 % in O3/H2O2/UV. Phytotoxicity tests revealed a noticeable reduction in the effluent toxicity, demonstrating the feasibility of these processes in realistic conditions as tertiary treatment.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 12